Fibrosis is an excessive wound-healing process induced by repeated or chronic tissue damage due to persistent external stimuli [1,2,3,4]. It can occur in a variety of solid organs or tissues and accounts for 45% of all-cause mortality worldwide [5,6]. Organ fibrosis, which affects the ...
nucleotide and nucleoside receptors, ATP release channels, and nucleoside transporters. Because of its immunomodulatory function, this system is critically involved in the pathogenesis of multiple sclerosis (MS) and its best-characterized animal model, experimental autoimmune encephalomyelitis...
The Ovarian Granulosa Cell as a Follicle-Stimulating Hormone Target Tissue 来自 Springer 喜欢 0 阅读量: 68 作者:B Kessel,XC Jia,JB Davoren,AJW Hsueh 摘要: The ovarian follicle is the basic functional unit of the ovary, and is comprised of an outer layer of theca cells, separated by a ...
On the other hand, GSPT1 immunostaining was not observed in the vascular tissue. Next, the relationship between GSPT1 expression and overall survival was examined in patients with glioblastoma. We measured the mRNA expression levels of 87 human glioblastoma specimens using real-time reverse ...
The effect of set-up uncertainties, contour changes, and tissue inhomogeneities on target dose-volume histograms Understanding set-up uncertainty effects on dose distributions is an important clinical problem but difficult to model accurately due to their dependence o... BCJ Cho,MV Herk,BJ Mijnheer...
This review may aid clinical and basic research on AMPK, which may be a novel drug candidate for hepatic fibrosis. INTRODUCTION Fibrosis, the formation of excess fibrous connective tissue in organs, is a major cause of morbidity and mortality worldwide. Fibrosis is a reactive or reparative ...
stimulate insulin secretion from pan- creatic β-cells but the binding of these drugs to peroxisome proliferator-activated receptor-γ (PPARγ) enhances the expres- sion of the glucose transporter and increases insulin sensitivity in target tissues such as, adipose tissue and skeletal muscle[29]. ...
We must first differentiate between epithelial and mesenchymal cells to better understand metastasis. Epithelial cells exhibit apical-basal polarity and are tightly attached to one another, which is essential for epithelial tissue. A transmembrane glycoprotein E-cadherin is one of the most important signa...
Jin L, Jin H, Zhang G, Xu G (2000) Changes in coagulation and tissue plasminogen activator after the treatment of cerebral infarction with lumbrokinase. Clin Hemorheol Microcirc 23:213–218 CAS PubMed Google Scholar Joo SS, Won TJ, Kim JS, Yoo YM, Tak ES, Park SY, Park HY, Hwang ...
Maintaining balanced copper levels is crucial for proper cellular metabolism. Copper deficiency can lead to Menkes disease, a rare disorder marked by developmental abnormalities, neurodegeneration, hypopigmentation, and connective tissue defects [20]. Conversely, excessive copper accumulation in the liver ca...