Return the primary external storage directory where this application's OBB files (if there are any) can be found. (Inherited from ContextWrapper) OpPackageName Return the package name that should be used for android.app.AppOpsManager calls from this context, so that app ops manager's uid...
1)Transcriptome input file in FASTA format. Note: For technical reasons, the labels of FASTA sequences must be unique numbers (no other characters). Sondovač will check the labels, and if they are not in an appropriate form, a copy of this input file with correct labels will be create...
GTSF1 is also sufficient to potentiate the catalytic activity of MIWI. Adding purified recombinant GTSF1 (Extended Data Fig.4b) to MIWI piRISC increased the rate of target cleavage by MIWI 19–100-fold for three different piRNA sequences (Fig.3a–cand Extended Data Fig.4c). First, the addi...
miRNAs are post-transcriptional regu- lators that bind to complementary sequences on target messenger RNA transcripts (mRNAs), resulting in trans- lational repression and gene silencing1. miRNAs are considered to be a major group of functional non-coding RNAs (ncRNAs) that bind to mRNAs, ...
Noninvasive detection of high-risk adenomas using stool-derived eukaryotic RNA sequences as biomarkers. Gastroenterology. 2019;157(3):884-887. doi:10.1053/j.gastro.2019.05.058PubMedGoogle ScholarCrossref 16. Barnell EK, Kang Y, Barnell AR, et al. Multitarget stool RNA test ...
Variable names must be unique within a query batch or stored procedure. Error - There is already an open DataReader associated with this Command which must be closed first. Error - This project references NuGet package(s) that are missing on this computer Error - This SqlTransaction has ...
The code generator is based on the assumption that the instruction selector will use an optimal pattern matching selector to create high-quality sequences of native instructions. Alternative code generator designs based on pattern expansion and aggressive iterative peephole optimization are much slower....
unique to that protein. In the PRM method all fragmentation products are monitored for the subsequent analysis. To quantitate the peptide an isotopically labeled reference peptide with the same sequence is used. Thetarget peptidesare then selected by the mass spectrometer and fragmented where several...
Compared to small-molecule drugs and antibody drugs, CRISPR therapy has the unique advantage of directly targeting the nucleic acid sequences of previously undruggable targets. However, non-specific targeting of gRNAs, which might introduce undesired edits, causes unexpected cell genotoxicity. And it ...
Considering off-target toxicity, a core focus of this manuscript, longer ASOs generally seem advantageous due to a ostensible reduction in the theoretical number of off-target sequences/sites compared to shorter ones54. Indeed, this 18-nt long ASO has a unique sequence with no full match or ...