Long-term tamoxifen has generally only few and usually mild adverse side effects. More serious, potentially life-threatening toxicities are rare. Aside from the ocular effects, most documented side effects appear to be related to the estrogenic properties of tamoxifen, for instance, thrombembolic ...
While pain relievers such as acetaminophen and NSAIDs can help relieve the pain, NSAIDs themselves have their side effects and should not be taken long-term unless under a doctor's advice. Continue reading Is it common to lose hair AFTER stopping tamoxifen? Unfortunately, there is a lack of...
Studies are being done to learn more about the long-term benefits and risks of using tamoxifen citrate tablets to reduce the chance of getting breast cancer.What are the possible side effects of tamoxifen citrate tablets?The most common side effect of tamoxifen citrate tablets is hot flashes. ...
However, the development of persistent side effects from chronic administration of tamoxifen remains a concern. The objective of this project was to investigate the effect of long-term tamoxifen therapy (2 years) on the plasma lipoprotein concentration and lipid transfer activity in postmenopausal women...
(tamoxifen citrate) for girls aged two to 10 years with McCune-Albright Syndrome and precocious puberty have not been studied beyond one year of treatment. The long-term effects of NOLVADEX (tamoxifen citrate) therapy in girls have not been established.In adults treated with NOLVADEX (tamoxifen ...
Long-term treatment, possibly of indefinite duration, is being evaluated. Compliance with long-term therapy will depend largely on the nature and severity of tamoxifen's side effects. We evaluated the symptoms associated with tamoxifen therapy in 140 postmenopausal women with axillary node negative ...
Long-term effects of continuing adjuvant tamoxifen to 10 years versus stopping at 5 years after diagnosis of oestrogen receptor-positive breast cancer: ATL... Background For women with oestrogen receptor (ER)-positive early breast cancer, treatment with tamoxifen for 5 years substantially reduces the...
However, long-term data from clinical trials have failed to demonstrate a cardioprotective effect.[46] For some women, tamoxifen can cause a rapid increase in triglyceride concentration in the blood.[citation needed] In addition there is an increased risk of thromboembolism especially during and ...
Side effects are minor and tolerable in chronic use of therapeutic dosage. Although its efficacy in treatment and prevention of breast cancer is established, concerns about increase in risk of endometrial cancer in long-term use still exist. It also disrupts fertility. Tamoxifen has been attributed...
Despite their overall effectiveness, however, long term usage of these treatments reveal moderate to severe side effects. Both drugs are shown to increase disease-free survival, and to reduce cancer-related mortality. At the same time, cardiovascular disease has emerged as the single greatest non-...