However, the effects of adjuvant tamoxifen therapy on bone mineral density (BMD) in premenopausal patients with breast cancer remains uncertain. Tamoxifen would have a potential impact of premenopausal BMD on health. The aim of this meta-analysis was to assess this in premenopausal women with ...
CYP2D6 polymorphisms may predict occurrence of adverse effects to tamoxifen: A preliminary retrospective study ratne MA, Hewage AS, Sundralingam T (2017) CYP2D6 polymorphisms may predict occurrence of adverse effects to tamoxifen: a preliminary retrospective study. ... I Wickramage,K Tennekoon,MAY...
Proc Natl Acad Sci USA 102: 3738 – 3743 Dillon MF, Stafford AT, Kelly G, Redmond AM, McIlroy M, Crotty TB, McDermott E, Hill AD, Young LS (2008) Cyclooxygenase-2 predicts adverse effects of tamoxifen: a possible mechanism of role for nuclear HER2 in breast cancer patients. Endocr ...
Background: The level of adherence of various pharmacological therapies in chronic diseases varies, but is predominantly low. With tamoxifen (TAM), 23% and... V Ziller,M Kalder,US Albert,... - 《Annals of Oncology》 被引量: 297发表: 2009年 The Effects of Neoadjuvant Anastrozole (Arimidex...
15.Kedar, RP, Bourne, TH, Collins, WP, Campbell, S, Powles, TJ, Ashley, S, et al.. Effects of tamoxifen on uterus and ovaries of postmenopausal women in a randomised breast cancer prevention trial.Lancet1994;343:1318–21.https://doi.org/10.1016/s0140-6736(94)92466-x. ...
Breast Cancer - Targets and Therapy Dovepress open access to scientific and medical research Open Access Full Text Article ORIGINAL RESEARCH CYP2D6 polymorphisms may predict occurrence of adverse effects to tamoxifen: a preliminary retrospective study This article was published in the following Dove ...
Adverse Effects Adverse effects of danazol that reflect inhibition of the pituitary-ovarian axis include menstrual disturbances and amenorrhoea (occasionally persistent), hot flushes, sweating, reduction in breast size, changes in libido, vaginal dryness and irritation, emotional lability, and ...
Postmenopausal osteoporosis represents a failure of the response by which bone cells adapt bone mass and architecture to be sufficiently strong to withstan... Lee,K. - 《Journal of Endocrinology》 被引量: 218发表: 2004年 Beneficial effects of the anti-oestrogen tamoxifen on systemic lupus erythema...
Tamoxifen and AIs have different effects on cardiac health in patients with breast cancer. Tamoxifen has demonstrated favourable cardiovascular effects such as a reduction in total and low-density lipoprotein cholesterol (LDL-C) levels, an increase in high-density lipoprotein cholesterol levels, and a...
Aromatase inhibitors (AIs) are routinely used in the adjuvant treatment of women with hormone receptor-positive early breast cancer. Patients who receive AIs have an increased risk of bone loss and arthralgia compared with those treated with tamoxifen. In addition to the effects of AIs, the popul...