TGR5 Receptor Agonist (CCDC) 是一种有效的 Takeda G蛋白偶联受体 (TGR5、GPCR19) 激动剂。 产品性质 英文别名 (English Synonym) TGR5 Receptor Agonist 中文名称 (Chinese Name) / 靶点 (Target) TGR5 通路 (Pathway) GPCR/G Protein CAS号 (CAS NO.) 1197300-24-5 分子式 (Formula) C18H14Cl2...
Introduction:TGR5 belongs to G-protein coupled receptor family, that mediates bile acid signaling. Activation of TGR5 by bile acids triggers intestinal glucagon-like peptide-1 secretion, whereby pharmacological activation of TGR5 constitutes a promising incretin-based strategy for the treatment of ...
Hodge, R. J.,Nunez,etc.Therapeutic potential of Takeda-G-protein-receptor-5 (TGR5) agonists. Hope or hype?[J].2016,18(5).Hodge RJ, Nunez DJ. Therapeutic potential of Takeda-G-protein- receptor-5 (TGR5) agonists. Hope or hype? Diabetes Obes Metab 2016; 18: 439-43. (Review)...
INT-777 prevents cognitive impairment by activating Takeda G protein-coupled receptor 5 (TGR5) and attenuating neuroinflammation via cAMP/ PKA/ CREB signaling axis in a rat model of sepsis - ScienceDirectSepsis-associated encephalopathyTGR5INT-777...
INT-777 prevents cognitive impairment by activating Takeda G protein-coupled receptor 5 (TGR5) and attenuating neuroinflammation via cAMP/PKA/ CREB signaling axis in a rat model of sepsisSepsis-associated encephalopathyTGR5INT-777Cognitive impairment...
P3B.18: INT 767 – a novel dual Farnesoid-X Receptor (FXR) and Takeda G-protein-coupled Receptor-5 (TGR5) agonist attenuates intestinal ischemia reperfusion injuryEmilio Canovai, Ricard Farr茅, Alison Accarie, Gert De Hertogh, Tim Vanuytsel, Jacques Pirenne, Laurens Ceulemans Leuven I...