作者选择 iBMDMs 是因为它们是一种成熟且常规使用的细胞类型,用于研究细胞死亡和炎症的先天免疫机制,并且它们为大规模研究提供了几乎无限的细胞供应。作者使用全基因组 CRISPR-Brie 文库 (#73633, Addgene) 制备的经过验证的慢病毒颗粒感染表达 Cas9 的 iBMDM(图 1A)。Brie 库为每个基因携带四个 gRNA,覆盖整个基因...
PROLIFERATIVEviabilitycolonydownstreamObjective To study the effect of transforming growth factor-βactivated kinase-1 (TAK1) gene silencing on the proliferation and apoptosis of Kasumi-1 cells induced by arsenic trioxide (As2O3) .Methods Acute myeloid许锦霞China Medical Abstracts (Internal Medicine)...
半滑舌鳎TRAF6基因和TAK1基因的克隆及表达分析 陈燕, 樊琳, 刘田田, 刘跃中, 李赞, 张全启 中国海洋大学 海洋生命学院, 山东 青岛 266003 摘要: 本研究通过同源克隆和RACE 技术获得了半滑舌鳎(Cynoglossus semilaevis )肿瘤坏死因子受体相关因子 6 (tumor necrosis factor receptor-associated factor 6, TRAF6)和...
Prolonged inhibition or deletion of the TAK1 gene in neurons was, however, not protective. Short-term, but not prolonged inhibition of TAK1 interfered with the activation of p38/MAPK and JNK by OGD, the induction of the pro-oxidative genes Cox-2, Nox-2, and p40(phox), and the ...
Abstract:ObjectiveTodeterminetheinfluenceandmechanismofTAK1genesilencingbyRNAinterferenceonprolifera- tionanddrugsensitivityofBGC823cells.MethodssiRNAtargetingTAK1mRNAandnegativecontrolweretransfectedinto BGC823cellsbyLipofectamine2000.Cellproliferationabilityanddrugsensitivitytodocetaxel,oxaliplatinand5-fluoroura- ...
Gene Symbol TAK1 Gene ID (NCBI) 6885 RRID AB_2882898 Conjugate Unconjugated Form Liquid Purification Method Protein G purification UNIPROT ID O43318 Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Storage Conditions Store at -20°C. Stable for one year after shipment. ...
¥2080.00元/format:100ul 目录号:IPH2348 库存:现货 规格 产品信息 Catalog No. :IPH2348 Reactivity:Human;Mouse;Rat Applications:WB; IHC-p; ELISA Gene Name:MAP3K7 Protein Name:Mitogen-activated protein kinase kinase kinase 7 Human Gene Id:6885 ...
Gene ID (NCBI) 6885 Conjugate CoraLite® Plus 750 Fluorescent Dye Excitation/Emission Maxima Wavelengths 755 nm / 780 nm Form Liquid Purification Method Protein A purification UNIPROT ID O43318 Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. Storage Conditions Store...
Gene Name: MAP3K7 Protein Name: Mitogen-activated protein kinase kinase kinase 7 Human Gene Id: 6885 Swiss-Prot: O43318 Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Source: Polyclonal, Rabbit Dilution: WB: 1:500-1:2000 IHC: 1:100-1:300 ELISA:...
Google Share on Facebook MAP3K7 (redirected fromTAK1) Acronyms MAP3K7 A gene on chromosome 6q15 that encodes a MAPK kinase kinase belonging to a protein kinase signal transduction cascade. MAP3K7 plays a key role in the cascades of cellular responses triggered by environmental changes, as we...