The synthetic deoxyoctanucleotide d(G-G-G-G-T-C-C-C) crystallizes as an A-type DNA double helix containing two adjacent G · T base-pair mismatches. The structure has been refined to an R-factor of 14% at 2.1 resolution with 104 solvent molecules located. The two G · T mismatches...
Since this variant virus retains its capacity to transform T-cells in vitro, and since a pX product is suspected to be important in transformation, we have determined the nucleotide sequence of the entire pX region of this virus for comparison to the prototype HTLV-I. In addition, the region...
2.1.132 Part 1 Section 17.4.19, headers (Header Cells Associated With Table Cell) 2.1.133 Part 1 Section 17.4.20, hidden (Hidden Table Row Marker) 2.1.134 Part 1 Section 17.4.21, hideMark (Ignore End Of Cell Marker In Row Height Calculation) 2.1.135 Part 1 Section 17.4...
Amino acid sequences, deduced from nucleotide sequences, were characterised in silico using Expert Protein Analysis System42 (ExPASy). For expression analysis, one-month-old S. brachiata seedlings were transferred to a hydro- ponic system (½ MS with 8/16 h dark/light cycle at 25 °C) ...
Third, Vav, a nucleotide exchange factor for small GTPases, is anchored indirectly to LAT. This initiates a pathway that degrades IκB, freeing nuclear factor κB (NF-κB) (see Fig. 10.21C) to enter the nucleus. 6. The signal ultimately reaches the cytoskeleton via Vav, which catalyzes ...
After initial relaxation of the TTH interfaces, OAD0 is free for its nucleotide cycle and the energy from ATP hydrolysis is consumed to release OAD0 from B-tubule, rotate the motor domain and move it one step forward (Fig. 7c). Due to the forward movement, this in turn relaxes the ...
Fig. 5. The genome-wide networks of covarying nucleotide sites. (A) The 12 top scoring pairs (top 2.7%; see panel B) form three networks involving different types of SNPs (nodes) defined by color in Fig. 1 and numbered according to Fig. 3A. Each edge is provided with its support va...
Genetic engineering of crop plants has been successful in transferring traits into elite lines beyond what can be achieved with breeding techniques. Introduction of transgenes originating from other species has conferred resistance to biotic and abiotic
(Fig.3G, Additional file9: Table S7). The CDR3 sequences of the hyperexpanded clones were not related between both patients (Additional file9: Table S7). All other expanded clones in biopsy were closely related to the hyperexpanded clone with single-nucleotide substitutions within each patient...
The nucleotide and amino acid sequences of the anti-TRBC1-antibody binding epitope are shown on the right. Extended Data Fig. 4 Anti-TRBC1-SG3249 kills TRBC1+ cells in vivo. a, b, Flow cytometry to assess Jurkat cells (CD3 + , GFP + , top right quadrant) on day 205, ...