T-LGL leukemiadoi:10.1038/S41375-019-0471-3Klara KleinAgnieszka Witalisz-SieprackaBarbara MaurerDaniela PrinzGerwin HellerNicoletta LeidenfrostMichaela Prchal-MurphyTobias SuskeRichard MorigglVeronika SexlLeukemia
Adult T cell–like lymphoma/leukemia Angioimmunoblastic lymphoma Angiotropic lymphoma Intestinal T cell lymphoma Anaplastic large cell lymphoma MALT,Mucosa-associatedlymphoid tissue;LGL,large granular lymphocyte;NK,natural killer. Read full chapterView PDFExplore book...
(PCTLD-1) • T-Cell Large Granular Lymphocytic Leukemia (LGLL-1) • Adult T-Cell Leukemia/Lymphoma (ATLL-1) • T-Cell Prolymphocytic Leukemia (TPLL-1) • Extranodal NK/T-Cell Lymphoma, nasal type (NKTL-1) • Supportive Care (LYMP-A) • Lugano Response Criteria for Non-...
T-cell large granular lymphocytic leukemia (T-LGL) Chronic lymphoproliferative disorders of NK cells (provisional) Aggressive NK-cell leukemia Adult T-cell leukemia/lymphoma This review discusses the main clinical and therapeutic aspects of primary nodal PTCLs such as peripheral T-cell lymphoma not ot...
Clonal CD8+/T-cell receptor (TCR)αβ+ T-cell large granular lymphocyte (T-LGL) proliferations constitute the most common subtype of T-LGL leukemia. Although the etiology of T-LGL leukemia is largely unknown, it has been hypothesized that chronic antigen
Additionally, six months after starting R2, flow cytometry revealed the emergence of an LGL-like population (45% of a CD3+, CD8+, CD57+, CD2+, CD5-, CD7- population). Finally, when R2 was resumed, the patient developed B symptoms compatible with disease recurrence. He then began Epco...
1373 Introduction LGL leukemia is associated with cytopenias and expansion of clonally-derived mature cytotoxic CD8+ lymphocytes. The etiology of LGL leukemia is currently unknown, however, T cell activation, loss of lymph node homing receptor L-selectin (CD62L), and increased accumulation of T ce...
(T-LGL) leukemia, and human T-cell lymphotropic virus I (HTLV-I)-associated adult T-cell leukemia-lymphoma (ATLL) [41]. However, no responses were observed in T-ALL patients, and the shared expression of CD52 among normal and malignant T-lymphocytes, expose patients to dangerous effects ...
dog; GL lymphoma; hepatic lymphoma; hepatosplenic lymphoma; LGL lymphoma; toceranib1. Introduction Canine hepatosplenic T-cell lymphoma (HSTCL) is a lymphoma centered in the liver and spleen without significant involvement of peripheral lymph nodes and is thought to arise from cytotoxic ɤδ T-...
LGL白血病是一种罕见的血液系统恶性肿瘤,主要影响成年人,分为克隆性和反应性两类,诊断基于血液学检查、骨髓活检和免疫表型分析,治疗方法包括化疗、免疫抑制治疗和造血干细胞移植,预后因个体差异而异。 大颗粒淋巴细胞白血病(LGL)是一种罕见的白血病,主要影响成年人,其特征是外周血中存在大颗粒淋巴细胞(LGL)。LGL可分...