CD4(+) T helper cells and the role they play in viral control. J Mol Med. 2002;80(7):397–405. View this article via:Norris, P. J.; Rosenberg, E. S. CD4(ϩ) T helper cells and the role they play in viral control. J. Mol. Med. 2002, 80(7), 397- 405. (Epub. 2002 ...
当然,CD4+T细胞亚群众多,我们只介绍了三种常见的Th细胞亚群。Treg细胞,虽然也属于CD4+T细胞,但腕儿太大,我们有必要单独开一章。 参考文献: [1]Mosmann, T.R., et al., (1986) Two types of murine helper T cell clone. I. Definition according to profiles of...
1.Benjamin Schmiedel et al. Single-cell eQTL analysis of activated T cell subsets reveals activation and cell-type-dependent effects of disease-risk variants. Science Immunology, 2022, doi:10.1126/sciimmunol.abm2508. 2.LJI team uncovers new su...
成熟T细胞根据是否表达CD4或CD8:可分为CD4 T细胞和CD8 T细胞。 根据T细胞在免疫应答中的功能:可分为辅助性T细胞(helper T cell, Th)、细胞毒性T细胞(cytotoxic T cell,Tc )和调节性T细胞(regulatory T cell,Tr或Treg)。 Part 1 根据T细胞的分化状态 初始T细胞(naive T cell):是没有接受过抗原刺激的成熟T细胞...
成熟T细胞根据是否表达CD4或CD8:可分为CD4 T细胞和CD8 T细胞。 根据T细胞在免疫应答中的功能:可分为辅助性T细胞(helper T cell, Th)、细胞毒性T细胞(cytotoxic T cell,Tc )和调节性T细胞(regulatory T cell,Tr或Treg)。 Part 1 根据T细胞的分化状态
CD4+ T细胞和B细胞的相互作用是产生保护性抗体反应的基础,也是有害自身免疫性疾病发展的基础。最近对人体组织和血液样本的研究建立了一个新的CD4+ B辅助T细胞亚群,称为外周辅助T细胞(peripheral helper T, Tph)细胞。不像T滤泡辅助细胞(Tfh),它与淋巴器官内的B细胞相互作用,Tph细胞提供帮助B细胞在发炎的组织。Tph...
T helper (Th) cells are CD4+T cells that play a central role in the adaptive immune system, by facilitating the activity of other immune cells – especially antigen-presenting cells (APCs) such as B cells, macrophages, anddendriticcells – through the release of cytokines and chemokines. They...
cells (PIC-seq) and find that CD4+PD-1+CXCL13+T cells are a major interacting hub with antigen-presenting cells in the tumor microenvironment of human non-small cell lung carcinoma. We define this clonally expanded, tumor-specific and conserved T-cell subset as T-helper tumor (Tht) cells...
et al. Long-lived T follicular helper cells retain plasticity and help sustain humoral immunity. Sci. Immunol. 5, eaay5552 (2020). Article PubMed Google Scholar Tubo, N. J. et al. Single naive CD4+ T cells from a diverse repertoire produce different effector cell types during infection....
大家好,今天跟大家分享这篇题为 Single-Cell RNA-Sequ encing Reveals Peripheral T Helper Cells Promoting the Development of IgG4-Related Disease by Enhancing B Cell Activation and Differen tiation(单细胞RNA测序揭示外周T辅助细胞通过增强B细胞活化和分化促进IgG4相关疾病的发展)这种疾病最初被认为主要影响胰...