t cells cd4 memory 翻译 T细胞CD4+记忆细胞在人类免疫系统中扮演着非常重要的角色,以执行多种功能。这些细胞可以识别和记忆出对身体有益或有害的抗原,并对它们进行反应。这就是为什么研究T细胞CD4+记忆细胞非常重要的原因。那么T细胞CD4+记忆细胞到底是什么?它们的功能又是什么呢?下面我们将分步骤进行阐述。 1. ...
CD4 T cells activated in the mesenteric lymph node mediate gastrointestinal food allergy in mice. Blazquez AB, Zhang S, Mayer L, Sampson HA, Berin MC: CD4 T cells activated in the mesenteric lymph node mediate gastrointestinal food allergy in mice... Knight,Adina,Kay,... - 《American ...
Number of unique TCRβ sequences per cluster: TN cells, 59; CD161- TM cells, 54; CD161+CD117- TM cells, 37; CD161+CD117+ TM cells, 51; Naive Treg cells, 29; Memory Treg cells, 50. (b) Hierarchical clustering of CD4+ T subpopulations based on individual V-J rearrangements in ...
T cell developmental defects in the activated CD4+T cell-treated FTOC. Fetal thymic organ cultures were set up with d16 fetal thymuses (CD45.2+) pre-incubated without or with 2 × 104naive or activated CD4+T cells (CD45.1+). The cultures were harvested and analysed at day 12. (...
Memory CD4+ T cells do not induce graft-versus-host disease. J Clin Invest, 112 (2003), pp. 101-108 View in ScopusGoogle Scholar 9 BJ Chen, X Cui, GD Sempowski, C Liu, NJ Chao Transfer of allogeneic CD62L- memory T cells without graft-versus-host disease. Blood, 103 (2004), ...
neoplastic cells in the lymph nodes and/or increased tumor burden in metastatic disease activate CD8(+) T-cell-mediated antitumor immunity to self-epitopes... M Russo,GP Martelli,GL Rana - 《Cancer Research》 被引量: 153发表: 2003年 The role of CD4+CD25+ immunoregulatory T cells in the ...
Methods Here, using magnetic beads and fluorescence-activated cell sorting, we extensively phenotype the Tck effector cells and conclude that effector function resides within the CD4+CD45RO+, CCR7-, CD49dhigh population, and that these cells are derived from the effector memory CD4+ T cells in...
activated CD4+T cells or poly (I:C). Naive CD4+T cells were stimulated with anti-CD3/CD28 antibodies alone or in combination as indicated for 48–72 h. A STING inhibitor (H-151) or STING agonist (2′3′-cGAMP) was added for the last 8 h of culture where indicated. The cells ...
Importantly, although tissue-resident CD32+CD4+ memory cells were enriched with translation-competent reservoirs, most of it was detected in memory CD32-CD4+ T cells. Our findings support that CD32 labels highly activated/exhausted memory CD4+ T-cell subsets that contain only a small proportion ...
Staphylococcal enterotoxin A (SEA) is a potent stimulator of CD4+ and CD8+ T cells, the immunotoxic action of which remains unclear. We investigated the in vitro effects of SEA on freshly isolated human peripheral blood lymphocytes depleted of CD8+ T cells. Proliferation and flow cytometry analy...