Prognostic Factors in Childhood T-Cell Acute Lymphoblastic Leukemia: A Pediatric Oncology Group Study. Blood 1990;75(1):166-73.Shuster JJ, Falletta JM, Pullen DJ, Crist WM, Humphrey GB, Dowell BL, Wharam MD, Borowitz M: Prognostic factors in childhood T-cell acute lymphoblastic leukemia: A ...
peptides from the intracellular lymphoid-specific enzyme terminal deoxynucleotidyl transferase (TdT), presented in the context of HLA-A*02:01, specifically eliminate primary acute lymphoblastic leukemia (ALL) cells of T- and B-cell origin in vitro and in three mouse models of disseminated B-ALL....
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive type of blood cancer that accounts for about 15% of pediatric and 25% of adult acute lymphoblastic leukemia (ALL) cases. It is considered as a paradigm for the multistep nature of cancer initiation and progression. Genetic and ...
Clinically, it is highly invasive and patients have a poor long-term prognosis. ETP-ALL originates from early thymic progenitors (ETP), and its gene mutation profile is different from typical T cell acute lymphoblastic leukemia (T-ALL). Such patients have poor response to conventional first-...
Acute lymphoblastic leukemia (ALL) ALL is often fatal, with a dismal prognosis in r/r cases, particularly older patients [49]. The introduction of CAR-T cell treatment has transformed the clinical management of r/r B-cell ALL. Thus, despite significant progress, this disease remains an insurm...
It has been nearly half a century since angioimmunoblastic T-cell lymphoma (AITL) was characterized in the early 1970’s. Our understanding of the disease has dramatically changed due to multiple discoveries and insights. One of the key features of AITL
similar, whereas adult T-cell leukemia/lymphoma (ATLL) represents a high proportion of T- and NK-cell lymphomas in Japan. When ATLL is excluded, four countries (Thailand, Taiwan, Korea, and Japan) exhibit very similar patterns of subtype distribution of T- and NK-cell lymphomas. Extranodal...
More than 430 thousand new cases of the disease and more than 165 thousand deaths are registered annually. At the same time, 16 thousand new diagnoses of bladder cancer per year are made in Russia, on average 6 thousand patients die. Prognosis of morbidity IARC predicts 28.4 million new ...
The prognosis of haploidentical hematopoietic stem cell transplantation in infants and patients under 3 years old with acute leukemia 2024, Clinical Transplantation Incidence, Risk Factors, Characteristics, and Outcome of Chronic Graft Versus Host Disease in Children Undergoing Haploidentical Peripheral Blood ...
risk signature. Additionally, real-time qPCR and the HPA database corroborated the mRNA and protein expression patterns of signature genes in LUAD tissues. In summary, this research yielded an innovative T cell marker gene-based signature with remarkable potential to prognosis and anticipate ...