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Impaired T cell development inSatb1cKO animals is associated with changes to the transcription programs as previously documented17,27. Here and in our accompanying publication54, we have described the vast transcriptional deregulation in theSatb1fl/flCd4-Cre+animals. Stranded total RNA sequencing revea...
T细胞（T lymphocyte）起源于骨髓，然后转移到胸腺中发育成熟。成熟的T细胞经淋巴管、外周血和组织液等在...
T cell (Treg) expansion and control core body temperature in response to environmental fluctuations. Mechanistically, innate PLZF+γδ T cells produced tumor necrosis factor and interleukin (IL) 17 A and determined PDGFRα+and Pdpn+stromal-cell production of IL-33 in adipose tissue. Mice ...
f. CAR-T cell expansion during co-culture with CD276+ Capan-1 target cells Full size image CD276 dash CAR-T demonstrated enhanced pancreatic tumor control and improved expansion ability compared with conventional CAR-T in vivo. Animal experiments are crucial for the development of new human ...
The enhanced alternative Grip1 exon in thunder cells (Figure S9) encodes a palmitoylated, membrane-associated Grip1b form of Glutamate Receptor Interacting Protein 1, a multi-PDZ-domain intracellular scaffolding protein that plays a key role in cell-matrix interactions during development, neuronal ...
Ellmeier W, Sawada S, Littman DR: The regulation of CD4 and CD8 coreceptor gene expression during T cell development. Annu Rev Immun. 1999, 17: 523-54. 10.1146/annurev.immunol.17.1.523. Article CAS PubMed Google Scholar Bosselut R, Zhang J, Ashe JM, Kopacz JL, Samelson LE, Singer...
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