Specialized subpopulations of CD4+ T cells survey major histocompatibility complex class II–peptide complexes to control phagosomal infections, help B cells, regulate tissue homeostasis and repair or perform immune regulation. Memory CD4+ T cells are po
MagniSort™ Human CD4 Memory T cell Enrichment Kit 设计通过磁性阴性分选分离 CD4 记忆 T 细胞。它经过优化,可利用生物素化的抗体混合物和链霉亲和素包被的磁珠从正常人类外周血单核细胞中分离人类 CD4 记忆 T 细胞。非目标细胞将由抗体结合,随后结合至磁珠,将其放入磁力架中,溶液中会留下完整的悬浮 CD4 ...
(2012). Memory CD4+ T cells: fate determination, positive feedback and plasticity. Cellular and molecular life sciences : CMLS 69, 1577-1583.Yamane H, Paul WE. Memory CD4+ T cells: fate determination, positive feedback and plasticity. Cell Mol Life Sci. 2012; 69:1577-1583. [PubMed: ...
该试剂盒用于从人PBMC中快速、高效分离未经经标记的记忆性CD4 T细胞。生物素化的CD45RA、CD8、CD14、CD16、CD19、CD56、CD36、CD123、抗TCRγ/δ和CD235a抗体共同孵育PBMC,随后用抗生物素微珠进行磁珠标记,从而去除初始T细胞、CD8 T细胞、B细胞、NK细胞、γ/δ T细胞、单核细胞、DC细胞、粒细胞、血小板和红系...
MagniSort™ Human CD4 Memory T cell Enrichment Kit 设计用于通过阴性选择实现 CD4 记忆 T 细胞的磁性分离。它已经过优化,可利用生物素化抗体混合物和链霉素亲和素包被磁珠从正常人外周血单核细胞中分离人 CD4 记忆 T 细胞。非目标细胞会由抗体结合,随后结合至磁珠,若将其放入磁场,溶液中会留下完整的游离 CD4...
In the literature one marker used to characterise CD4+ T-cell differentiation is CD45RC and we offer Mouse anti Rat CD45RC MCA53G in various formats. “CD4 T cells are phenotypically divided by the expression of high and low molecu...
Memory-like CD4+ T cells had high expression of Ki-67, indicative of cell division, and CD5, a surrogate marker of TCR avidity, and produced the cytokines IFN-γ and IL-2. Pathway analysis revealed a differentiation trajectory associated with cellular activation and proinflammatory effector ...
Summary CD4 + T follicular helper (Tfh) cells provide the required signals to B cells for germinal center reactions that are necessary for long-lived antibody responses. However, it remains unclear whether there are CD4 + memory Tcells committed to the Tfh cell lineage after antigen clearance. ...
5.2.3 Other T cell subsets Memory T cells are T cells that have previously encountered their antigen and may be either CD4+ or CD8+ cells. They can be further subdivided into stem memory, central memory, effector memory, or tissue-resident memory T cells and are characterized by their expre...
7、记忆T细胞(Memory T cell,Tm),有记忆特异性抗原刺激的作用。T细胞在体内存活的时间可数月至数年。其记忆细胞存活的时间则更长。 其中,Th细胞又被称为CD4+细胞,因为其在表面表达CD4(cluster of differentiation 4)。通过与MHCⅡ(主要组织相容性复合体,major histocompatibility complex)递呈的多肽抗原反应被激活。