Systemic sclerosis (SSc) is an autoimmune disease and a disabling condition that reduces life expectancy. Disease heterogeneity is a hallmark of SSc and classification has been hard to establish. Moreover, within the SSc spectrum, subsetting according to the extent of skin involvement has been ...
Systemic sclerosis (SSc) is a generalised autoimmune disease, of yet unknown origin, with two major clinical subsets: the limited (lcSSc) and the diffuse cutaneous (dcSSc) forms, which can be distinguished by the extent of skin involvement, the autoantibody profile and the pattern of organ inv...
Olivier Sitbon23, Vincent Sobanski1, Marie‑Elise Truchetet24 , Luc Mouthon14* and Collaborators Abstract Systemic sclerosis (SSc) is a generalized disease of the connective tissue, arterioles, and microvessels, characterized by the appearance of fibrosis and vascular obliteration...
Systemic lupus erythematosus (SLE or Lupus; OMIM 152700) is an immune-mediated disease associated with a lower life expectancy due to an increased risk of major infections and renal and cardiovascular complications [1,2] Like other rheumatic diseases, such as Sjögren’s syndrome, systemic sclero...
Systemic sclerosis (SSc) is a generalised autoimmune disease, which causes morbidity and reduced life expectancy. Recently evidence has been accumulating that immunosuppressive treatment in an early stage of the disease could improve sur... MC Vonk,LEV Die,MM Snoeren,... - 《Annals of the Rheuma...
ObjectiveAlthough diffuse cutaneous systemic sclerosis (dcSSc) is associated with a reduction in life expectancy, there are no validated prognostic models for determining 5-year mortality in patients with dcSSc. The objective of this study was to derive and validate a rule for predicting 5-year mo...
Background Systemic Sclerosis (SSc)-heart disease (SSc-HD), although often clinically silent, significantly reduces the life-expectancy in these patients [1]. The cardiac magnetic resonance (CMR) is recognized useful tool for the diagnos... P Ruscitti,ED Cesare,P Cipriani,... - 《Annals of ...
Systemic sclerosis (SSc) is a chronic, systemic disease characterized by fibrosis of the skin and internal organs, vasculopathy, and auto-immune activation. On the top of severe organ involvement such as interstitial lung and myocardial fibrosis, pulmonary hypertension, and renal crisis, individuals ...
, multiple sclerosis (MS), diabetes, myocardial infarction, thyroditis and different types of neurological disorders, among others [15–23]. Various routes of administration of MSCs, including intravenous (i.v.) [24], intraarterial [25] ...
Systemic sclerosis (also known as scleroderma) is a multisystem disease that is subclassified according to the degree of skin involvement as diffuse or limited cutaneous. The former is associated with a greater degree of visceral disease and carries a worse prognosis. The limited cutaneous form is...