Introduction There is growing evidence to support SACT 30-day mortality rate as a key metric for assessing quality of cancer care and a key indicator of avoidable harm to patients from SACT due therapy-related or poor patient selection factors. This has been established for solid organ ...
99 Patient experiences of atezolizumab subcutaneous formulation compared to intravenous in Newcastle, and the impact on services delivering systemic anti-cancer treatments Lung Cancer Volume 200, Supplement 1, February 2025, Page 108209 Purchase options CorporateFor R&D professionals working in corporate orga...
Immunotherapy has revolutionized cancer treatment, but efficacy remains limited in most clinical settings. Cancer is a systemic disease that induces many functional and compositional changes to the immune system as a whole. Immunity is regulated by interactions of diverse cell lineages across tissues. Th...
Expert Review of Anti-infective TherapyMahner S, Prieske K, Grimm D, Trillsch F, Prieske S, von Amsberg G, et al. Systemic treatment of vulvar cancer. Expert Rev Anticancer Ther. 2015;15:629-37.Mahner, S., Prieske, K., Grimm, D., Trillsch, F., Prieske, S., von Amsberg, ...
Anti-tumour inflammatory cytokines are highly toxic when administered systemically. Here, in multiple syngeneic mouse models, we show that the intratumoural injection of recombinantly expressed cytokines bound tightly to the common vaccine adjuvant alumi
Systemic treatment in EGFR-ALK NSCLC patients: sec- ond line therapy and beyond. Expert Rev Anticanc. 2014; 14:807-815.Karachaliou N, Rosell R. Systemic treatment in EGFR-ALK NSCLC patients: second line therapy and beyond. Cancer Biol Med 2014;11:173-81....
These data identify the presence of ERP57 crucial for the translocation of CRT and to induce immunogenic cell death which will activate a anti-cancer immune responses.doi:US20090004172 A1Obeid, Michel SarkisUS
treatment outcomeantineoplastic combined chemotherapy protocolsColorectal cancer alone accounts for around 200,000 deaths in Europe and represents a significant health problem. Although about fifty percent of patients are cured by surgery alone, the other half will eventually die due to metastatic disease,...
Anti‐Th/ToAnti‐Rpp25cancersystemic sclerosisILDAutoantibodies in systemic sclerosis (SSc) can help stratify patients into more clinically‐relevant subsets (reviewed in (1)). We read with interest the study of 804 adult SSc by Mecoli et al. (2), which represents the one of the largest ...
This study reports on patient, tumour-related, and treatment-related factors associated with 30-day mortality after systemic anticancer treatment. We studied the diverse populations of patients with breast and lung cancer in England throughout 2014 using data from the newly available Systemic Anti-Can...