The systemic treatment of cancer is the major focus of cancer management. In treatment of some tumours such as childhood cancers, lymphomas and testicular cancers, great progress has been made with the use of cytotoxic drugs. Despite the fundamental advances in understanding of the molecular basis ...
Systemic Treatment for Hepatobiliary Cancers in First and Later Lines: Applying the Latest Data 11:30 AM - 1:00 PM Eastern Time (ET) In-person Private Event -- Sidney Kimmel Comprehensive Cancer Center Learn More January 31 2023 Systemic Treatment for Hepatobiliar...
Cancer is a disease of aging.1 Currently 50% of all malignancies occur in individuals 65 and over1 and by the year 2030 older individuals will account for 70% of all neoplasms.With the aging of the population the management of cancer in the older person with chemotherapy is beoming ...
treatment outcomeantineoplastic combined chemotherapy protocolsColorectal cancer alone accounts for around 200,000 deaths in Europe and represents a significant health problem. Although about fifty percent of patients are cured by surgery alone, the other half will eventually die due to metastatic disease,...
Prostate cancer is a leading cause of cancer mortality in adult men. The majority of patients have subclinical systemic disease at diagnosis and will eventually require systemic therapy for palliation of symptoms. Recent development of new hormonal treatment options (e.g., gonadotropin-releasing ...
Immunotherapy has revolutionized cancer treatment, but efficacy remains limited in most clinical settings. Cancer is a systemic disease that induces many functional and compositional changes to the immune system as a whole. Immunity is regulated by interactions of diverse cell lineages across tissues. Th...
In the last few decades, proliferative markers have been broadly evaluated as prognostic and predictive factors for early stage breast cancer patients. Several papers evaluating one or more markers have been published, often with contradictory results. As a consequence, there is still uncertainty about...
Cytotoxic chemotherapy, hormonal therapy and molecular targeted therapy are the three major classes of drugs used to treat breast cancer. Imaging modalities such as computed tomography (CT), magnetic resonance imaging (MRI), 18F-FDG positron emission tom
Safety and Efficacy of Vandetanib As Systemic Treatment for Patients with Advanced and Progressive Medullary Thyroid Cancer (Mtc) Aim : Vandetanib has demonstrated efficacy in advanced MTC in a large phase III trial (NCT00410761). However, little evidence is available on safety and efficacy of ...
More information:Marta Vaz Batista et al, Systemic treatment for brain metastasis in HER2- positive advanced breast cancer: what have we learned so far?,Oncotarget(2023).DOI: 10.18632/oncotarget.28435 Journal information:Oncotarget