Nasal administration: a tool for tomorrow's systemic administration of drugs. Drug Develop Indust Pharmacy, 1993, 19(1&2), pp. 101-122.Duchěne D, Ponchel G. Nasal administration: a tool for tomorrow's systemic administration of drugs. Drug De- velopment and Industrial Pharmacy 1993; 19:...
Systemic administration of analgesic drugs is still the most widely used method for providing pain relief in acute painful situations. Opioids may be selected on the basis of their physicochemical characteristics and their diffusion index to the brain. But in clinical practice, their very steep concen...
Systemic administration of analgesic drugs is still the most widely used method for providing pain relief in acute painful situations. Opioids may be selected on the basis of their physicochemical characteristics and their diffusion index to the brain. But in clinical practice, their very steep concen...
Round window administration of gentamicin: a new method for the study of ototoxicity of cochlear hair cells Damage to inner ear sensory hair cells after systemic administration of ototoxic drugs has been documented in humans and animals. Birds have the ability to... Kathrin,R,Husmann,... - 《...
Strategies to provide a protective effect towards an intestinal pre-systemic metabolism are based on the co-administration of enzyme inhibitor being optimally immobilized on unabsorbable and undegradable polymeric excipients in order to keep them concentrated there where an inhibitory effect is needed. ...
AdministrationAdminister estradiol orally, intravaginally, percutaneously by topical application of transdermal system, and by topical application of a gel, emulsion, or transdermal spray to the skin.Administer estradiol acetate orally or intravaginally.Administer estradiol cypionate and estradiol valerate IM...
Performances of cationic lipid formulations for intravenous gene delivery to mouse lungs have been previously reported. We report in this study that cationic phosphonolipids, when appropriately formulated, can be good synthetic vectors for gene delivery to lung after intravenous administration. One of ou...
of IGF-II, like an injection given directly into the rat hippocampus (Chen et al, 2011), affects aversive memories in mice. S.c. injections were chosen because previous Neuropsychopharmacology studies have successfully used this route of administration of IGFs in different species to affect ...
Intranasal administration is a non-invasive route for drug delivery, which is widely used for the local treatment of rhinitis or nasal polyposis. Since drugs can be absorbed into the systemic circulation through the nasal mucosa, this route may also be used in a range of acute...
AdministrationAdminister orally (as a solution) or by IV infusion as an antidote for acetaminophen overdosage; administer by oral inhalation or intracheal instillation for mucolytic uses.Has been administered orally or IV for prevention of radiographic contrast media-induced nephropathy† [off-label]...