TPPA, FTA-ABS, EIA, CIA) using neonatal serum are not recommended owing to passive transfer of IgG antibodies, which react with the reagents in these tests. All infants born to mothers with syphilis should
benötigen keine wiederholten Liquoruntersuchungen. Bei HIV-infizierten Patienten kann eine persistierende Liquorpleozytose eher die Auswirkung von HIV sein als dass sie eine persistierende Neurosyphilis darstellt. Normale Liquor-Zellzahlen, negative Liquor- und Serum-Reagintestergebnisse und nega...
linked immuno-sorbent assay (ELISA) could be caused by hemolysis. The RPR had low sensitivity in suspected syphilis neonates, and the colloidal gold test (SYP) was suitable for emergency treatment. The treponema pallidum particle agglutination test (TPPA) was fit for the diagnosis of syphilis [...
1. Performance Characteristics of dual HIV/syphilis POCTs for syphilis compared to reference TPPA assay (site-specific data). 12879_2024_9463_MOESM2_ESM.docx Supplementary Material 2: Fig. 2. Performance Characteristics of dual HIV/syphilis POCTs for HIV compared to reference assays (site-...
for syphilis, each with their own method of detecting the presence of the disease. Some of the most common types include enzyme-linked immunosorbent assays (ELISAs), rapid plasma reagin (RPR) tests, and treponemal-specific tests such as the T. pallidum particle agglutination (TPPA) test. ...
Although the CSF Venereal Disease Research Laboratory (VDRL) remains a mainstay of diagnostic testing for neurosyphilis, using a higher titer cutoff (greater than 1:320) for the Treponema pallidum particle agglutination assay (TPPA) from the CSF may improve the utility of the TPPA as a ...
Also Known As: Venereal Disease Research Laboratory, VDRL, Rapid Plasma Reagin, RPR Test, RPR Titer, Fluorescent Treponemal Antibody Absorption Test, FTA-ABS, Treponema pallidum Particle Agglutination Assay, TPPA, Microhemagglutination Assay, MHA-TP, Darkfield Microscopy, Automated Immunoassays for ...
The Syphilis Rapid Test (Whole Blood/Serum/Plasma) has correctly identified specimens of a seroconversion panel and has been compared to a leading commercial TPPA Syphilis test using clinical specimens. The results show that the relative sensitivity of the Syphilis Rapid Test (Whole Blood/Seru...
However, a TPPA titer cutoff of >1:640 in the CSF has been suggested as a realistic threshold level for diagnosing neurosyphilis in highly suspicious patients who are VDRL-negative, especially if a serum treponemal test is positive.[120][129][130] ...
A test for syphilis was requested, which came back as positive for total antibodies, Immunoglobulin M, trepo- nema pallidum particle agglutination (TPPA) and rapid plasma reagent (RPR: Titre > 1:128). Full syphilis treat- ment was commenced, with an injection of long-acting benzylpenicillin as...