Nontreponemal antibody tests should be used for screening, either the Venereal Disease Research Laboratory (VDRL) or rapid plasma reagin (RPR) test. Treatment of maternal syphilis is critical to prevent congenital infection: 70‐100% of infants born to untreated mothers will be infected vs 1‐2%...
Early neurosyphilis typically affects the vasculature and meninges. The CSF is almost always positive for the nontreponemal Venereal Disease Research Laboratory (VDRL) or rapid plasma reagin (RPR) testing, as well as treponemal antibody assays in early neurosyphilis.[41]Meningeal neurosyphilis usually ...
A positive VDRL test result may indicate the presence of active or previously treated syphilis. In this study, the VDRL test was used to determine the presence of active syphilis in patients. All patients also underwent a test for absorption of fluorescent treponemal antibody (FTA-ABS) to ...
16.Ngan W, Chiu PK, Chung HY. Primary Sjogren syndrome masquerading as a false-positive venereal disease research laboratory and fluorescent treponemal antibody absorption test in an elderly woman. Journal of the American Geriatrics Society. 2014;62(9):1817-1818. DOI: 10.1111/jgs.13013 ...
This study found no false-negatives for any test. One fair-quality retrospective study (n = 139) evaluated the prozone phenomenon using rapid plasma reagin (RPR) testing.18 The prozone phenomenon occurs when undiluted serum containing a high titer of nonspecific antibody (as may occur in ...
Because of the possibility of false-positive results, confirmation for any positive or equivocal nontreponemal test result should follow with a treponemal test, such as the fluorescent treponemal antibody-absorption (FTA-ABS), microhemagglutination assayT pallidum(MHA-TP),T pallidumhemagglutination (TPHA...
HIV-1 antibody was detected by enzyme-linked immunosorbent assay [ELISA] (Vironostika® HIV-1Microelisa System; bioMerieux, Durham, NC, USA), and positive tests were confirmed by Western blot test (HIV Blot 2.2 WBTM, Genelabs Diagnostics, Singapore). Rapid plasma reagin (RPR) test (RPR,...
Harding AS, Ghanem KG. The performance of cerebrospinal fluid treponemal-specific antibody tests in neurosyphilis: a systematic review.Sex Transm Dis. 2012;39(4):p.291–7. doi:10.1097/OLQ.0b013e31824c0e62 (Open in a new window)PubMed(Open in a new window)Web of Science ®(Open in ...
The RPR continued to be used as a confirmatory test as well as for monitoring response to therapy. In Calgary, the secondary confirma- tory test was either the fluorescent treponemal antibody absorption test (FTA-ABS) or the line immunoassay (INNO-LIA). Repeat syphilis episodes were identified...
Routine lumbar puncture was performed in all these patients, and 6 mL of CSF was collected for routine examination, biochemistry, detection of IgG index, TRUST, TPPA, cerebrospinal fluid-venereal disease research laboratory test and fluorescent treponemal antibody absorption test (FTA-ABS). At the...