Claim 1: a procedure for preparing a pyrazole derivative 3 - amino - 4 - substituted formula (1) wherein R2 is selected from the group consisting alquenilo, R9, rent, alquinilo, CF3, heterociclilo, heterociclilalquilo, halogen, haloalquilo, aryl, arylalkyl, heteroarilalquil Or, alquin...
A novel -enaminonitrile of 1-(6-p-tolyl-pyridazin-3-yl)-pyrazole derivative 2 was formed using (6-p-tolyl-pyridazin-3-yl)-hydrazine ( 1 ) and 2-ethoxymethylenemalononitrile. The -enaminonitrile derivative 2 was in turn used as a precursor for the preparation of pyrazoles ( 4 , 6 ...
Synthesis of Novel Chiral Diazole Derivative Ligands for the Enantioselective Addition of Diethylzinc to Benzaldehyde The high-pressure-promoted reaction of epoxides with pyrazoles and imidazoles provided access to a variety of chiral diazole derivative ligands such as 11... - 《Journal of Organic ...
14], [15], and allowed to react with 6-aminouracil in ethanol in the presence of a catalytic amount of TEA to produce 6-amino-2-(3-chloroquinoxalin-2-ylthio)pyrimidin-4(3H)-one (3), which was refluxed in DMF to give the corresponding thiazolo[4,5-b]quinoxaline-4-one derivative 4...
Corrosion inhibition properties of schiff base derivative against mild steel in HCl environment complemented with DFT investigations ArticleOpen access02 June 2023 Corrosion inhibition of mild steel in 1 M HCl by pyrazolone-sulfonamide hybrids: synthesis, characterization, and evaluation ...
The new chemical entity, water-soluble pyrazole curcumin derivative (PyCurOAc) was designed, synthesized and characterized for the purpose of inhibition of AGE formation. The compound showed an excellent in vitro AGEs inhibition activity than curcumin itself as well as the standard. Further, the ...
The synthesis of the title compounds was achieved using 1-phenyl-5-(pyrrol-1-yl)-1 H -pyrazole-3-carboxylic acid azide as starting material. The latter compound was allowed to react with alcohols and amines to afford the corresponding carbamates and urea derivatives. Alkaline hydrolysis of the...
Synthesis and Antitumor Activity of Some Novel Pyrazole and Thienopyrimidine Derivatives. Aly,H. M. Phosphorus, Sulfur, and Silicon . 2009Aly,H. M.Synthesis and Antitumor Activity of Some Novel Pyrazole and Thienopyrimidine Derivatives. Phosphorus, Sulfur, and Silicon . 2009...
Green synthesis and antifungal activities of novel 3-(trifluoromethyl)-4, 5-dihydro-1 H-furo[2,3-c]pyrazole derivatives J. Heterocyclic Chem., 57 (2020), pp. 2904-2910 View articleCrossrefView in ScopusGoogle Scholar Tan et al., 2018 W. Tan, Q. Li, F. Dong, J. Zhang, F. Luan,...
In 1H NMR spectra of compounds 3a-p, the N–H proton of benzimidazole moiety resonates in more down field region i.e. around δ 13 ppm. The plausible mechanism for the formation of benzimidazole derivative is suggested in Scheme 5. Download: Download high-res image (92KB) Download: ...