The aminopyrazole compounds of Formula IV above are obtained by ring-closing the corresponding compounds of Formula III above at temperatures above room temperature. N - Acetyl - N1 - (α - cyano - # - ethoxyacryloyl)urea is obtained by reacting cyanoacetic acid with urea in the presence of...
Synthesis of Some Pyrazolo[3, 4]pyrimidine Derivatives for Biological Evaluationβ-enaminonitrileacyclic nucleosidespyrazolepyrazolo[3,4-d]pyrimidinepyrazolo-[4,3-e]-[1,2,4]triazolo[4,3-c]pyrimidineA novel -enaminonitrile of 1-(6-p-tolyl-pyridazin-3-yl)-pyrazole derivative 2 was formed ...
Synthesis and biological studies of some imidazolinone derivatives A Series of 4-(1-Aryl-5-oxo-2-phenyl-2-imidazolin-4-yl) metheno-5-chloro-3-methyl-1-phenyl-3-pyrazole) were synthesised and tested for their antibacterial, antiinflammatory and analagesic activities. Some of the compounds show...
[4,5-b]quinoxaline derivatives 5–14 via the reaction with 2-chlorobenzaldehyde, 2-chlorocyclohex-1-enecarbaldehyde, 2-chlorobenzoic acid, 2,4-dichlorobenzoic acid, 5-chloro-3-methyl-1-phenyl-1H-pyrazole-4-carbaldehyde, 2-chloro-4,6-dimethylnicotinonitrile, α,β-unsaturated ketones and iso...
This novel reaction selectively gave 3 H -pyrazolo[4,3- f ]quinolin-9-yl acetates, in high yield, rather than 3 H -pyrazolo[4,3- f ]quinoline-8-carboxylate derivatives. This procedure has the advantages of mild reaction conditions, high yields, metal-free catalyst, and high regio-...
J.A facile one pot synthesis of pyrano[2,3-c]pyrazole derivatives under microwave irradiation.Synthetic Communications. 2002Zhou JF, Tu SJ, Zhu HQ, Zhi SJ (2002) A facile one pot synthesis of pyrano[2,3-c]pyrazole derivatives under micriwave irradiation. Synth Commun 32:3363-3366...
The synthesis of the title compounds was achieved using 1-phenyl-5-(pyrrol-1-yl)-1 H -pyrazole-3-carboxylic acid azide as starting material. The latter compound was allowed to react with alcohols and amines to afford the corresponding carbamates and urea derivatives. Alkaline hydrolysis of the...
(3H)-ylidene)methyl)-1H-pyrazol-3-yl)-2H-chromen-2-one derivatives (5a–l) by Claisen–Schmidt condensation of 3-(6-substituted-2-oxo-2H-chromen-3-yl)-1-(4-substituted)-1H-pyrazole-4-carbaldehyde derivatives (4a–l) with 5,6-dimethoxy-2,3-dihydro-1H-inden-1-one at reflux ...
This was modified by sulphanilic acid to develop network polymeric structure having free –SO3H group and it was applied as a solid heterogeneous catalyst for the synthesis of benzimidazole and its derivatives. Benzimidazole and its derivatives have been the area of much research interest due to ...
of its good predictivity and intuitive image. For example, Liet al.10reported a CoMFA 3D-QSAR model about a series of pyrazole derivatives againstRhizoctonia solani. Similarly Yanget al.11reported fungicidal activity and 3D-QSAR study of phenylhydrazine substituted tetronic acid derivatives. Motivated ...