贝克-维德曼综合征(Beckwith-Wiedemann syndrome,BWS)是一种以新生儿低血糖、巨大儿、大舌癌、偏侧发育过度、脐膨出、胚胎肿瘤(如肾母细胞瘤、肝母细胞瘤、神经母细胞瘤和横纹肌肉瘤)、内脏肿大、肾上腺皮质细胞瘤、肾脏异常(如髓质发育不良、肾髓质增...
Objectives: Beckwith-Wiedemann syndrome (BWS) is the most common overgrowth syndrome and has an incidence of 1/13,700. The majority of the cases are diagnosed after birth. Patients with BWS have an increased risk of neonatal hypoglycemia and embryonal tumors development in childhood. We wanted ...
Beckwith-Wiedemann syndrome is a rare congenital disorder. Early diagnosis, proper counselling of parents is essential because of significant risk of subsequent development of malignant tumours, associated with this syndrome. Association of cleft palate in this syndrome is extremely rare. Specific ...
伯韦综合征(Beckwith-WiedemannSyndrome,BWS)是与位于11号染色体短臂15区域印记基因簇表达异常相关的一种罕见疾病,具有先天性过度生长及有癌症倾向,发病率约为1/13700,男女发病率相同。以过度生长、巨舌、巨大儿和腹壁缺损(脐膨出/脐疝)为...
Beckwith-Wiedemann syndrome (BWS) refers to an overgrowth condition characterized by a larger than normal physical build during childhood. For some affected individuals, the body parts on one side are larger which causes an uneven appearance. The growth typically slows down by age 8 and the ...
Beckwith–Wiedemann syndrome • This syndrome consists of hyperplastic fetalvisceromegalyinvolving the kidney,adrenal cortex, pancreas, gonads, and liver,hemihypertrophy,macroglossia,abdominal wall defects(omphalocele,umbilical hernia, and diastasis recti), ear pits or creases,microcephaly, mental retarda...
The different molecular causes of Beckwith-Wiedemann syndrome (BWS) have varying tumor and health risks. Due to the stratification of risk, it is important for patients with BWS to be tested for genetic and epigenetic alterations on chromosome 11 to appropriately assess health concerns. BWS is a...
Beckwith-Wiedemann syndrome (BWS) is a growth disorder characterized by macrosomia, macroglossia, visceromegaly, embryonal tumors (e.g., Wilms tumor, hepatoblastoma, neuroblastoma, and rhabdomyosarcoma), omphalocele, neonatal hypoglycemia, ear creases/pits, adrenocortical cytomegaly, and renal abnormalities...
必应词典为您提供Beckwith-Wiedemann-Syndrome的释义,网络释义: 贝克威斯韦德曼氏症;综合征;贝克威斯综合症;
Beckwith-Wiedemann syndrome (BWS) is a model disorder for the study of imprinting, growth dysregulation, and tumorigenesis. Unique observations in this disorder point to an important embryonic developmental window relevant to the observations of increased monozygotic twinning and an increased rate of epig...