Access to the synapse multi-organ dataset: 1. Sign up in the [official Synapse website](https://www.synapse.org/#!Synapse:syn3193805/wiki/) and download the dataset. Convert them to numpy format, clip the images within [-125, 275], normalize each 3D image to [0, 1], and extract ...
Access to the synapse multi-organ dataset: 1. Sign up in the [official Synapse website](https://www.synapse.org/#!Synapse:syn3193805/wiki/) and download the dataset. Convert them to numpy format, clip the images within [-125, 275], normalize each 3D image to [0, 1], and extract ...
The proper physiological functioning of most eukaryotic cells requires their assembly into multi-cellular tissues that form organized organ systems. Cells of the immune system develop in bone marrow and lymphoid organs, but as the cells mature they leave these organs and circulate as single cells. ...
accurate, and triggered by a combination of depolarization and calcium signals that lead to synaptic vesicle fusion. On the other hand, the endocytotic machinery is slower and more diverged. For example, after a massive synaptic vesicle exocytosis from the Torpedo electric organ, the synaptic...
The decalcified bone, lateral wall, Reissner’s membrane, and tectorial membranes were dissected away from the organ of Corti. For whole mount preparation, cochleae were then divided into 4 pieces and cryoprotected in 30% sucrose for 30 minutes prior to freezing on dry ice. The frozen pieces...
Recent research has uncovered several examples connecting autophagy and hormonal-type regulations interacting between organ systems in non-cell autonomous regimes. For instance, Atg18 acts non-cell autonomously both in neurons and in intestines to firstly, maintain the wild-type lifespan of C.elegans ...
Each had a distinct pattern of motility on stroma, with CD56dim NK cells moving in rapid, linear tracks, CD56bright NK cells moving in shorter, multi-directional tracks and CD56neg NK cells demonstrating minimal migration (Fig. 1a; Supplementary Movies 1–3). To ensure that antibody used to...
Like a plug and a socket, a nerve and a muscle fiber mesh at the neuromuscular junction. New work by Nishimune et al published in the Journal of Cell Biology reveals that an extracellular matrix protein called laminin shapes both sides of the junction to
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