SV40 large T antigen expression driven by col2a1 regulatory sequences immortalizes articular chondrocytes but does not allow stabilization of type II collagen expression. Experimental Cell Research 1999;249:248-59.Steimberg N,Viengchareun S,Biehlmann F,et al.SV40 Large T antigen expression driven ...
Recombinant protein encompassing a sequence within the C-terminus region of SV40 Large T. The exact sequence is proprietary. 偶联物 Unconjugated 形式 Liquid 浓度 0.5 mg/mL 纯化类型 Antigen affinity chromatography 保存液 PBS, pH 7, with 20% glycerol 内含物 0.025% ProClin 300 ...
1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemESV40 large Tantigen NLSCat. No.: HY-P0310分式: CHNOS分量: 1401.7Sequence: Cys-Gly-Gly-Gly-Pro-Lys-Lys-Lys-Arg-Lys-Val-Glu-AspSequence Shortening:CGGGPKKKRKVED作靶点: Others作通路: Others储存式: Please store the p...
This result suggests that a specific DNA sequence (OriP) or palindromic structures could play a role in this integration process. This represents the first fully characterized site of integration of an EBV vector in human cells. The transient expression of the SV40 large T antigen in H-G1 ...
Name质粒/病毒名称:SV40 large T-antigen (CMV, GFP-Bsd) lentivirusID编号:BioVector-LVP016-GBFunction用途:Map图谱:Sequence序列:Insert/Gene Type:Bacterial resistance原核抗性:Selection Marker真核筛选标记:Reporter荧光报告基因:供应商:BioVector NTCC质粒载体菌株细胞蛋白抗体基因保藏中心 电话:400-800-2947 http:...
The 5' flanking regions of the genes (U1 and U2) encoding the human U1 and U2 small nuclear RNAs (snRNAs) each contain sequences that bind specifically to the simian virus (SV40) large tumor antigen (T.Ag). Substitution of these sites with sequences that lack T.Ag-binding sites did no...
SV40 large T-antigen and human pleural mesothelioma DNA-like sequences of the p53 and pRB-inactivating simian virus 40 large T-antigen (SV40 LTag) have recently been found in mesotheliomas in the United Stat... K Dhaene,A Verhulst,EV Marck - 《Virchows Archiv An International Journal of Pat...
The 5′ flanking regions of the genes (U1 and U2) encoding the human U1 and U2 small nuclear RNAs (snRNAs) each contain sequences that bind specifically to the simian virus (SV40) large tumor antigen (T·Ag). Substitution of these sites with sequences that lack T·Ag-binding sites did...
而8例正常人脑组织均无Tag表达,二者差异显著(P<0.05);分别检测18例和15例Tag阳性瘤组织,均发现Tag可与p53,pRb形成特异性复合物.结论SV40Tag的表达与人脑肿瘤的发生有一定关系;SV40Tag与p53,pRb形成特异性复合物并导致其失活,可能是SV40致人脑肿瘤发生的一个重要机制Keywords:simianvirus40(SV40);largetumorantigen...
The parental line was created by immortalizing the primary cells by transfection with SV40 large T antigen. Transfection was done using conditioned medium from psiTEX cells (which produce a helper free replication defective retrovirus that carries the sequences for large T antigen and neomycin (G418...