Suzuki–Miyaura cross-coupling couplingreactions with low catalyst loading: a green and sustainable protocol in pure water. Fihri A,Luart D,Len C, et al. Dalton Transactions . 2011Fihri, A.; Luart, D.; Len, C.; Solhi, A.; Chevrin, C.; Polshettiwar, V. Suzuki-Miyaura cross-...
Suzuki反应(铃木反应),也称作Suzuki偶联反应、Suzuki-Miyaura反应(铃木-宫浦反应),是一个较新的有机偶联反应,该反应由A. Suzuki 和N. Miyaura在1979年首先报道,在有机合成中的用途很广,具强的底物适应性及官能团容忍性,常用于合成多烯烃、苯乙烯和联苯的衍生物,从而应用于众多天然...
Miyaura CrossCouplingReaction",suchasusingwaterasthesolvent, havebeenmade romGreenChemistry'sviewpoint.For example,ArB(OH)3 - Bu4N + ,generatedwhentetrabutyl- ammoniumbromideandarylboronicacidreactinwater, acceleratesthecross-couplingreaction(eq.4). 3) Thecross- couplingreactionsusingthewater-solublePd(...
Suzuki-Miyaura cross-coupling (Suzuki 偶联反应) 1. 定义: Suzuki反应是在零价钯催化下,芳基/烯基硼化物与芳基或烯基卤化物之间发生的交叉偶联反应,常用于构建C-C键,也称为Suzuki偶联反应或Suzuki-Miyaura偶联反应。 2.反应通式 3.反应机理 首先零价钯和卤化物发生氧化加成钯络合物1,在碱性作用下,可生成...
[5] Ruben Martin et al., Palladium-Catalyzed Suzuki-Miyaura Cross-Coupling Reactions Employing Dialkylbiaryl Phosphine Ligands. Acc. Chem. Res.2008, 41 , 1461. [6] Wenjun Tang et al., A General and Special Catalyst for Suzuki–Miyaura Coupling Processes. Angew. Chem. Int. Ed.2010, 49 ,...
A polymer-supported terpyridine Pd(II) complex was prepared and found to promote the Suzuki–Miyaura coupling reaction in water. Thus, terpyridine ligand was prepared from p-hydroxybenzaldehyde, propane sultone, and 2-acetylpyridine according to the reported procedures. Immobilization of terpyridine ligan...
Cross-coupling reactions, and the Suzuki reaction in particular, are among the widely used synthetic methods for creating new C-C bonds to form more complex molecules from smaller molecules. In the Suzuki reaction, or Suzuki–Miyaura reaction, an organoboron compound, and an organohalide are cr...
Chirik课题组合成了Phenoxyimine (FI)−nickel(II)(2-tolyl)(DMAP)化合物,并使用其作为预催化剂来催化(杂)芳基硼酸与烷基溴的C(sp2)−C(sp3) Suzuki−Miyaura交叉偶联反应。在5 mol% (MeOMeFI)Ni(Aryl)(DMAP)预催化剂的存在下,多种(杂)芳基硼酸和烷基溴(>50例)均可顺利实现转化,以33-97%的产率...
suzuki miyaura交叉偶联反应
In this work, we present the first examples of Suzuki–Miyaura cross-coupling reactions on meso-triaryl corroles with heteroaromatic boronic acids and esters, alkenylboronic acids, as well as a highly efficient method for the Suzuki–Miyaura of corroles with simpler boronic acids. 2. Results and...