Sulfonamides are combined with diaminopyrimidines such as trimethoprim (TMP) and pyrimethamine (PYM), which inhibit an essential step farther along the folate pathway. Because the potentiated sulfonamides are remarkably synergistic and nontoxic, they are commonly used in equine medicine. Their use is ...
Sulfonamides are the oldest synthetic antimicrobial drugs, which are still commonly used chiefly due to their broad spectrum of activity, high efficacy, easy synthesis, and low cost. Sulfonamides do not kill the bacteria rather they inhibit their ability to grow and replicate. Sulfonamides selectively...