Acute myeloid leukemia (AML) is an aggressive blood cancer with a poor prognosis. We report a comprehensive proteogenomic analysis of bone marrow biopsies from 252 uniformly treated AML patients to elucidate the molecular pathophysiology of AML in order to inform future diagnostic and therapeutic ...
Acute myeloid leukemia (AML) is an aggressive blood cancer with a poor prognosis. We report a comprehensive proteogenomic analysis of bone marrow biopsies from 252 uniformly treated AML patients to elucidate the molecular pathophysiology of AML in order to inform future diagnostic and therapeutic appro...
Cell of origin determines clinically relevant subtypes of MLL-rearranged AML. Leukemia. 2013; 27 :852–860. [ PubMed ]Krivtsov AV, et al. Cell of origin determines clinically relevant subtypes of MLL-rearranged AML. Leukemia. 2013;27(4):852–860. View this article via:...
Acute myelogenous leukemia (AML).Most AML subtypes are distinguished from other related blood disorders by the presence of more than 20% blasts in the bone marrow.,站酷海洛,一站式正版视觉内容平台,站酷旗下品牌.授权内容包含正版商业图片、艺术插画、矢量、视
OBJECTIVES: The objectives are (1) to investigate and identify potential risk factors (personal characteristics, lifestyle and environmental factors) of acute myeloid leukemia (AML), and (2) to explore the relationships between potential risk factors and AML subtypes according to the World Health Org...
Hodgkin lymphoma, not otherwise specified Nodular lymphocyte-predominant Hodgkin lymphoma Indolent B-cell lymphomas Follicular lymphoma Hairy cell leukemia Marginal zone lymphoma Waldenström’s macroglobulinemia Mantle cell lymphomas Mantle cell lymphoma
Cross-talk between leukemic and endothelial cells promotes angiogenesis by VEGF activation of the Notch/Dll4 pathway Angiogenesis is suggested to be important for leukemogenesis and chemosensitivity in acute myeloid leukemia (AML). The vascular endothelial growth factor (... J Zhang,J Ye,D Ma,......
leukemia (AML). The glucose metabolism metabolites lactate and pyruvate are elevated in AML patient serum samples, and are strong predictors of poor prognosis32. Yet, given the rather heterogeneous genetic landscape of AML, it appears likely that differences exist in metabolic reprogramming between ...
Adult Acute Erythroleukemia: An Analysis of 108 patients treated at a single institution Acute erythroleukemia (AML-M6) is an uncommon subtype of acute myeloid leukemia (AML); it is considered to have a poor prognosis. From January 1st, 1980 to... F Santos,S Faderl,G Garcia-Manero,......
Chromosomal rearrangements (CR) initiate leukemogenesis in approximately 50 % of acute myeloid leukemia (AML) patients; however, limited targeted therapies exist due to a lack of accurate molecular and genetic biomarkers of refractory mechanisms during treatment. Here, we investigated the pathological ...