Portela, A. & Digard, P. The influenza virus nucleoprotein: a multifunctional RNA-binding protein pivotal to virus replication. J. Gen. Virol. 83, 723–734 (2002). Article CAS PubMed Google Scholar Area, E. et al. 3D structure of the influenza virus polymerase complex: localization of ...
All proteins are made of chains of amino acids, and there are around 20 different kinds of these compounds. The shape of proteins is determined by the sequence of amino acids, but the way in which the chains fold up is so complex that predicting a protein’s structure from its...
Structures, Dynamics, and Functions of Viral Membrane Proteins by NMRProtein–membrane interactions play essential roles in a variety of cell functions such as signaling, membrane trafficking, and transport. Membrane-recruited cytosolic proteins... LG Basso,SH Park,AJ Costa-Filho,... - 《Biophysical...
Here we report that the cryo-electron microscopy structures of α-synuclein filaments from the brains of individuals with PD, PDD and DLB are made of a single protofilament (Lewy fold) that is markedly different from the protofilaments of MSA. These findings establish the existence of distinct ...
Internal structures determine the functions of the proteins. Many proteins have multiple densely folded sections called domains, usually containing over a hundred amino acid molecules, which function individually or collaboratively. AlphaFold2 can map out the overall shapes of protein domains, combined wit...
Studying the secondary structure of proteins leads to an understanding of the components that make up a whole protein, and such an understanding of the structure of the whole protein is often vital to understanding its digestive behaviour and nutritive value in animals. The main protein secondary ...
A protein, the specific dna - structures, and uses thereofTONEY, JEFFREYPIL, PIETERESSIGMANN, JOHNDONAHUE, BRIANKELLETT, PATTIBROWN, STEVENBRUHN, SUZANNELIPPARD, STEPHEN
structures of all-alpha type membrane proteins have made valuable contributions to understanding structure–function relationships in membrane proteins. These range from the first insights into the function of exciting individual proteins to an in-depth knowledge of protein function from entire biological ...
Thanks to the modular nature of ProteinTools, the addition of new applications will become an easy task. Given the current need to have these tools in a single, fast, and interpretable interface, we believe that ProteinTools will become an essential toolkit for the wider protein research ...
AI protein-folding algorithms solve structures faster than ever Subjects Proteomics Structural biology Machine learning Sign up to Nature Briefing An essential round-up of science news, opinion and analysis, delivered to your inbox every weekday. Email address Yes! Sign me up to receive the...