Stabilization of protein structures. Curr. Opin. Biotechnol. 8, 423-428.Lee, B., and G. Vasmatzis. 1997. Stabilization of protein structures. Curr. Opin. Biotechnol. 8:423-428.Lee B, Vasmatzis G (1997) Stabilization of protein structures . Curr Opin Biotechnol 8 : 423–428...
Crystal structures of the apoprotein and with bound saturated and unsaturated fatty acids. Crystals of the adipocyte lipid-binding protein which diffract to near atomic resolution have been obtained in Na/K phosphate buffer/precipitant system. Th... Xu ZH,DA Bernlohr,LJ Banaszak - 《Journal of ...
The well-balanced stability of protein structures allows large-scale fluctuations, which are indispensable in many biochemical functions, ensures the long-term persistence of the equilibrium structure and it regulates the degradation of proteins to provide amino acids for biosynthesis. This balance is stu...
Targeted protein degradation and stabilization are promising therapeutic modalities because of their potency, versatility and their potential to expand the druggable target space1,2. However, only a few of the hundreds of E3 ligases and deubiquitinases in the human proteome have been harnessed for th...
There were a couple of PDB structures in which no SCs could be identified. Most of these protein structures were solution NMR structures. Since the definition of SCs is very sensitive to the quality of the structure due to the hard limit of heavy atom distances, we prefer high resolution X...
Influence of sucrose on the thermal denaturation, gelation, and emulsion stabilization of whey proteins. The influence of sucrose (0-40 wt %) on the thermal denaturation and functionality of whey protein isolate (WPI) solutions has been studied. The effect of ... A Kulmyrzaev,C Bryant,DJ Mc...
These results suggest that it may be feasible to use multilayer assemblies of functional proteins and enzymesin high-temperature applications. 展开 关键词: Stabilization of the membrane protein bacteriorhodopsin to 140 ...C in two-dimensional films, Artículo ...
Structure elucidation of inactive-state GPCRs still mostly relies on X-ray crystallography. The major goal of our work was to create a new GPCR tool that would provide receptor stability and additional soluble surface for crystallization. Towards this ai
Though the problem of sequence-reversed protein folding is largely unexplored, one might speculate that reversed native protein sequences should be significantly more foldable than purely random heteropolymer sequences. In this article, we investigate how the reverse-sequences of native proteins might ...
Stabilization of triple‐helical structures of collagen peptides containing a Hyp‐Thr‐Gly, Hyp‐Val‐Gly, or Hyp‐Ser‐Gly sequencedoi:10.1002/bip.21625collagencrystal structureprotein stabilitytriple helixthreonineKenji OkuyamaKeita MiyamaTatsuya Morimoto...