(1998). Structure of Escherichia coli primase/single-strand DNA-binding protein/phage G4oric complex required for primer RNA synthesis. J. Mol. Biol. 276, 689-703.Sun W, Godson GN. Structure of the Escherichia coli primase/single-strand DNA-binding protein/ phage G4oric complex required for...
Related to DNA structure:DNA replication DNA A. adenine T. thymine C. cytosine G. guanine DNA (dē′ĕn-ā′) n. A nucleic acid that carries the genetic information in cells and some viruses, consisting of two long chains of nucleotides twisted into a double helix and joined by hydrogen...
The α-helix, β-sheet, and other secondary structures are combined in many ways in a protein. The combination of α- and β-strand produces various kinds of domains in proteins. Such independently folded domains may have structural-functional motifs that may be involved in DNA binding, as ...
We also show details of single-stranded DNA binding and propose a model for geminivirus capsid assembly. Results Structure of AYVV To address these questions, we determined the structure of AYVV using single particle cryo-EM (Fig. 1). AYVV (and, indeed, the majority of the Begomoviruses) ...
Characterization of single stranded nucleic acids by melting analysis of secondary structure using double strand-specific nucleic acid dye A novel method for characterizing nucleic acids. A nucleic acid is combined with a double stranded nucleic acid-specific dye to form a detectable complex between the...
E. et al. Human flap endonuclease structures, DNA double-base flipping, and a unified understanding of the FEN1 superfamily. Cell 145, 198–211 (2011). Article CAS PubMed PubMed Central Google Scholar Tsutakawa, S. E. & Tainer, J. A. Double strand binding-single strand incision ...
These restricted movements, when repeated through several amino acids in a chain, yield the two main types of protein secondary structure: the alpha (α) helix and the beta (β) strand. The α helix is shaped like a spiral staircase, with each step representing a single amino acid. Each...
The two strands of DNA run in opposite directions. These strands are held together by the hydrogen bond that is present between the two complementary bases. The strands are helically twisted, where each strand forms a right-handed coil, and ten nucleotides make up a single turn. The pitch of...
DNA Structure Watson and Crickproposed thatDNAis made up of two strands that are twisted around each other to form a right-handed helix. The two DNA strands areantiparallel, such that the 3ʹ end of one strand faces the 5ʹ end of the other (Figure 6). The 3ʹ end of each stra...
Among the various regulatory proteins identified to date, several single-stranded DNA (ssDNA)-binding proteins known as Purα and Purβ have been implicated in SMαA promoter repression in VSMCs and myofibroblasts by virtue of their strand-specific interaction with certain sequence elements present ...