Filoviruses, including Ebola virus, pose an increasing threat to the public health. Although two therapeutic monoclonal antibodies have been approved to treat the Ebola virus disease1,2, there are no approved broadly reactive drugs to control diverse fil
Zika virus (ZIKV), formerly a neglected pathogen, has recently been associated with microcephaly in fetuses1, and with Guillian–Barré syndrome in adults2. Here we present the 3.7 Å resolution cryo-electron microscopy structure of ZIKV, and show that the overall architecture of the virus ...
Doolittle, R.E, Hunkapiller, M.W., Hood, L.E., Devare, S.G., Robbins, K.C., Aaronson, S.A. and Antoniades, H.N.: Simian sarcoma virus oncogene, v-sis, is derived from the gene (or genes) encoding a platelet derived growth factor. Science221: 275–277, 1983. ArticlePubMedC...
2. Background 副粘病毒科是有包膜病毒,其中包括腮腺炎病毒、麻疹病毒、仙台病毒、新城疫病毒 (NDV)、人类呼吸道合胞病毒 (RSV)、副流感病毒 5 (SV5) 和人类副流感病毒1-4 (hPIV) ),该病毒家族的许多成员是重要的人类和动物病原体,并且已鉴定出新出现的致命副粘病毒。 副粘病毒与其他包膜病毒(例如流感病毒...
What structural protein of virus for? Protect the viral genome 01:45 Delivery of the genome 02:47 Definitionsof new terms subunit structural unit capsid envelope nucleocapsid 06:10 putting virus particles into perspective (scale) ...
W. (1964). The structure of ORF virus. Virology, 23,946.Nagington J, Newton AA, Horne RW (1964) The structure of Orf virus. Virology 23: 461–472Nagington, J., A. A. Newton, and R. W. Horne. 1964. The structure of Orf virus. Virology 23:461-472....
The structure of a human common cold virus (rhinovirus 14) and its structural and functional relations to other picornaviruses and plant viruses. The structure of a human common cold virus (rhinovirus 14) and its functional relations to other Picornaviruses. In Crystallography in Molecular Biology,...
In this paper, the structure of the hepatitis B virus, a detailed description, 翻译结果2复制译文编辑译文朗读译文返回顶部 翻译结果3复制译文编辑译文朗读译文返回顶部 This article first make a detailed introduction to the structure of the hepatitis b virus, ...
Influenza A viruses (IAVs) constitute a major threat to human health. The IAV genome consists of eight single-stranded viral RNA segments contained in separate viral ribonucleoprotein (vRNP) complexes that are packaged together into a single virus partic
Crystal structures of several flavivirus proteases were reported in free-enzyme form and in complex with inhibitors, all with a flexible linker covalently tethered between NS2B cofactor peptide (residues 49–97) and NS3 protease domain7. Here, we captured the active enzyme in one of its native ...