Repetitive propagation of action potentials destabilizes the structure of the myelin sheath - Padr贸n, Mateu - 1982 () Citation Context ... paranodal axoglial junctions thereby impacting the action potential [8]. Structural deformation of myelin following repetitive CAP propagation has been visualized...
Cytological studies by the Altmann-Gersh freezing-drying method, Anat - HOERR () Citation Context ...g Tissues were frozen in isopentane (2-methyl butane) maintained at --70 to --75°C by a mixture of dry ice and acetone or at about --150 to --165°C with liquid nitrogen as ...
The myelin sheath is an essential, multilayered membrane structure that insulates axons, enabling the rapid transmission of nerve impulses. The tetraspan myelin proteolipid protein (PLP) is the most abundant protein of compact myelin in the central nervous system (CNS). The integral membrane protein...
Observing the structure and regeneration of the myelin sheath in peripheral nerves following injury and during repair would help in understanding the pathogenesis and treatment of neurological diseases caused by an abnormal myelin sheath. In the present study, transmission electron microscopy, immunofluoresce...
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Zika virus (ZikV) infection during pregnancy can cause congenital Zika syndrome (CZS) and neurodevelopmental delay in infants, of which the pathogenesis remains poorly understood. We utilize an established female pigtail macaque maternal-to-fetal ZikV in
Due to the low capacitance of the myelin sheath, the axon potential transits between Ranvier nodes (small portions of axons not involved by the myelin sheath, where voltage-dependent sodium channels are located, allowing the entry of depolarizing current in the form of sodium ions), in a ...
Otherwise, this structure, which is prominent in wild-type myelin, is conspicuously absent. Redundant folding of some lamellae but not others may occur in the same sheath. These observations conform to those made previously on the isolated myelin segments that occur in the myelin-deficient rat ...
Briefly discuss the function(s) of axons, dendrites, and the role of Schwann cells in the formation of the myelin sheath. Describe the anatomy of the spinal cord and relate the anatomy to the movement of nerve impulses to ...
Sulfatides are sphingolipids found at the outer leaflet of the plasma membrane of most eukaryotic cells, and they represent the major lipid component (4–6%) of the myelin sheath in the mammalian nervous system (46). Sulfatides interact with several proteins specifically participating in hemostasis,...