- 《International Union of Biochemistry & Molecular Biology Life》 被引量: 115发表: 2006年 Allosteric Activation of the Phosphoinositide Phosphatase Sac1 by Anionic Phospholipids Sac family phosphoinositide phosphatases comprise an evolutionarily conserved family of enzymes in eukaryotes. Our recently ...
phospholipidsdegummingindustrial enzymesEnzymes of the phospholipase superfamily are involved in lipid metabolism, as well as regulation of membrane composition, cell signaling, and inflammation. This review provides an insight into the structure, functional properties, and biotechnological application of ...
On the other hand, the basic, catalytically active Asp49-PLA2s damage the sarcolemma by a mechanism that essentially relies on their ability to hydrolyse phospholipids [14], [23]. Both mechanisms converge in affecting the integrity of the sarcolemma rapidly after toxin injection, causing the ...
Glycosylphosphatidylinositol (GPI) molecules are complex glycophospholipids and serve as membrane anchors for tethering many proteins to the cell surface. Attaching GPI to the protein in the endoplasmic reticulum (ER) is catalyzed by the transmembrane GPI transamidase (GPIT) complex, which is essential...
Biochemistry of Platelet-Activating Factor: A Unique Class of Biologically Active Phospholipids I. Introduction In the autumn of 1979, three independent laboratories (1鈥 3) described the chemical structure of a new subclass of phospholipids that posse... F Snyder - 《Experimental Biology & Medicine...
Phosphatidylcholines and certain other phospholipids, as pure substances and as mixtures, can be dispersed in aqueous media to form unilamellar vesicles. The process by which these vesicles form in most instances depends on the bending and subsequent closure of an initially flat disc micelle. Under ...
Here, we use POPC/POPG lipids at a molar ratio of 9/1 and SMA polymers to form lipodisq nanoparticles. POPC is the most common phospholipid found in mammalian cell membranes, and POPG was chosen to mimic the 10–20 molar percent anionic phospholipids typically found in mammalian membranes [...
H. Erythrocyte morphology reflects the transbilayer distribution of incorporated phospholipids. J. Cell Biol. 108, 1375–1385 (1989). CAS PubMed Google Scholar Lee, A. G. A calcium pump made visible. Curr. Opin. Struct. Biol. 12, 547–554 (2002). CAS PubMed Google Scholar ...
Lipoproteins are complexes between a particular set of proteins (termed apoproteins) and lipids (phospholipids, triglycerides, cholesterol, and cholesterol esters). These lipids are transported throughout the body as the complex lipoproteins. Humans have nine different apoproteins of various molecular size...
Conserved lipid-binding sites in membrane proteins: a focus on cytochrome c oxidase. Curr. Opin. Struct. Biol. 17, 444–450 (2007). Article CAS PubMed PubMed Central Google Scholar Wenz, T. et al. Role of phospholipids in respiratory cytochrome bc1 complex catalysis and supercomplex ...