The weight ratio of lipid to polymer was varied and different lipodisq nanoparticle samples were characterized by solid-state NMR (SSNMR) and dynamic light scattering (DLS). Transmission electron microscopy (TEM) was also used to confirm the size and homogeneity of vesicles and lipodisq ...
Proofs of the structure of lipid coated nanoparticles (SMBV~TM) used as antigen carriers for vaccineSupramolecular Biovectors (SMBV~TM) have been described as multi-compartimental nanoparticles composed of a cationic cross-linked polysaccharide nanoparticle (PSC) which is surrounded by a lecithin/...
For the gas temperatures considered, evaporative cooling leads to droplet temperature below the melting point of the lipid solute. Thus, we conclude that control over nanoparticle size and structure, of thermolabile precursor materials suitable for drug delivery, can be achieved by controlling ...
The lipid nanoparticles were injected through intramuscular delivery to mice at a dose of 0.1 μg in 30 μL volume. hEPO levels were detected in the blood of the mice 6 and 24 h post injection with an ELISA assay. 2. Materials & methods 2.1. mRNA synthesis and lipid nanoparticle ...
The TCE swollen micellar microstructure, corresponding to a micellar microemulsion, formed via monolayer collapse transition, has a great potential of ordering nanoparticle and drug delivery as a result of encapsulating nanoparticles into the core of micellar microemulsions and transferring them from one ...
Electrostatically mediated liposome fusion and lipid exchange with a nanoparticle-supported bilayer for control of surface charge, drug containment, and de... The loading and containment of cargo within nanoparticles and their efficient delivery to cells represent a primary challenge in nanomedicine. We ...
adeno-associated virus (AAV), and adenovirus (Ad) vectors [43]. Viral vectors are especially appropriate vehicles for in vivo works, most commonly used for CRISPR system delivery. Reported on-viral vector systems include lipid nanoparticles, cell-penetrating peptides (CPPs), and gold nanoparticles...
structure, synthesis, toxicity, surface modification, and also possible new applications of these spherical polymers in biomedical fields as dendrimer-based ... N Taghavi Pourianazar,P Mutlu,U Gunduz - 《Journal of Nanoparticle Research》 被引量: 37发表: 2014年 Synthesis and Characterization of a ...
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cell–nanoparticle interactionsdrug delivery systemsliquid crystalline lipidsself‐assembled nanostructurestissue cytotoxicitySelf‐assembly of lipid‐based liquid crystalline (LLC) nanoparticles is a formulation art arising from the hydrophilic–lipophilic qualities and the geometric packing of amphiphilic lipid ...