产品名称:罗丹明固体脂质纳米粒(solid lipid nanoparticles,SLN) 产品简介: 罗丹明固体脂质纳米粒(SLN)是一种新型的纳米载体,结合了固体脂质和罗丹明荧光染料,广泛应用于药物递送、成像和治疗等领域。 1. 结构与合成 固体脂质纳米粒(SLN): SLN由固体脂质(如脂肪酸甘油酯、蜡等)制成,具有良好的生物相容性和...
(Solidlipidnanoparticles,SLN) InstituteofMateriaMedica Contents 概述 1 制备材料 2 制备方法 3 性质 4 脂质促吸收的机理 6 应用 5 InstituteofMateriaMedica SLN是近年来正在发展的一类新型纳米载药系统,它以长链饱和脂肪酸、脂 肪酸甘油酯等体内可以降解且具有良好生物相容性的天然或合成的类脂材料 为载体,将药物...
Solid lipid nanoparticles (SLNs) are the first generation of lipid nanoヽarriers. They were introduced in 1990 and have been investigated by pharmaceutical scientists for delivery of lipophilic drugs. Siekmann and colleagues developed a high﹑ressure homogenization technique to prepare SLNs, offering ...
Solid lipid nanoparticles (SLNTM, LipopearlsTM) are nanoparticles made from solid lipids by highpressurehomogenization. Incorporation of chemically labile active ingredients intothe solid lipid matrix protects against chemical degradation, which is shown for vitamin E. The SLN are physically stable in aq...
Solid lipid nanoparticles (SLNs) are lipid nanoparticles (LNPs), which have frequently been practiced. Suitable release rate, stability, and target delivery make SLNs a good alternative for colloidal carriers. SLNs are supposed to have great potential to deliver natural products with anti-parasitic...
Solid lipid nanoparticles (SLN) based on binary mixtures of liquid and solid lipids: a 1H-NMR study Int J Pharm 2000; 205(1-2): 15-21.V. Jenning, S. Gohla, Solid lipid nanoparticles (SLN) based on binary mixtures of liquid and solid lipids: a 1H-NMR study, Int. J. Pharm. (...
Drug delivery systems Solid lipid nanoparticles Nanocolloidal carriers Therapeutic agents Pharmacokinetics Lipids 1. Introduction During last three decades, nanotechnology has been introduced as a novel interdisciplinary field of science which initiated the explosion of research on the development of nanostructur...
Solid lipid particles (SLNs) are the stabilized drug delivery systems having solid lipids and surfactants as their building blocks. They are intended for increasing the solubility and ultimately the bioavailability of power water soluble drugs. Different methods have been reported for their production,...
are the high pressure homogenization and microemulsion technique; the drug incorporation and release profiles can be modified as a function of production parameters;the SLN can be used by different administration routes.Conclusions The solid lipid nanoparticles have broad prospects in the pharmaceutical ...
solid lipid nanoparticles (SLNs) have gained more importance owing to its benefits like affordable cost and safety, than other colloidal nanoparticles. SLNs were introduced in 1991 and consisted of a core of solid lipid with surfactants having a size not more than 1,000 nm24,25. The matrix ...