Within this tunnel, catalytic histidine and asparagine approach the lumen and instigate the transfer of the acetyl group from Ac-CoA to the glucosamine group of HS. Our study unveils a transmembrane acetylation mechanism that may help advance therapeutic strategies targeting lysosomal storage diseases. ...
Structure of the ADP-BeF3-bound ATPase at near-atomic resolution shows network of interactions between the ATPase and ADP-BeF3, which results in a close conformation with the ATPase lobe1 and lobe2 grasping nucleosomal DNA (Fig.2, Supplementary Fig.6). As the mimeticγ-phosphate of ATP, Be...
The lipopolysaccharide (LPS) is the major constituent of the outer leaflet of the outer membrane of Gram-negative bacteria. Its lipid A moiety is embedded in the membrane and serves as an anchor for the rest of the LPS molecule. The outermost repetitive
Structure of 1,6-bis(p-chlorophenyl)-3,4-diacetyl-1,5-hexaazadiene: a compound with a highly electrophilic N-acetyl group No abstract is available for this article. D Mackay,DD Mcintyre,NJ Taylor - 《Chemischer Informationsdienst》 被引量: 25发表: 1982年 ChemInform Abstract: STRUCTURE OF 1...
Orotidine 5'-phosphate (OMP) decarboxylase appears to act upon its substrate without the intervention of metals or other cofactors and without the formatio... CA Lewis,R Wolfenden - 《Biochemistry》 被引量: 16发表: 2007年 The crystal and molecular structure of 2'-acetyluridine-3',5'-cycloph...
select article Synthesis, spectroscopic, X-ray diffraction, antimicrobial and antitumor studies of Ni(II) and Co(II) complexes derived from 4-acetyl-5,6-diphenyl-3(2H)-pyridazinone and ethylenediamine Research articleAbstract only Synthesis, spectroscopic, X-ray diffraction, antimicrobial and antitumor...
Blots were incubated in 5% skimmed milk powder/TBST at room temperature for 1 h, and then they were incubated with the following antibodies in 5% BSA or 5% skimmed milk powder/TBST at 4 °C overnight: anti-histone H3 (1:1000; Abcam, ab1791), anti-acetyl-histone H3 (1:1000; ...
The crystal structure of bis(acetylacetonato)lead(II) and the structure of the acetylacetone solvated lead(II) ion in solution have been determined by single-crystal X-ray diffraction and large-angle X-ray scattering (LAXS), respectively. The acetylacetone is deprotonated and acts as a bidentate...
A unique feature of theTrv. strain 970 LH1 is that another histidine residue (His48) in the LH1 α-polypeptide, a residue absent from other purple bacterial LH1 α-polypeptides (Supplementary Fig.8a)21, also participates in hydrogen bonding with the C3-acetyl group of BChlsa(Fig.2c) in...
The crystal structure of π-cyclopentadienylbis(acetylacetonato)chlorozirconium(IV), π-C5H5(C5H7O2) 2ZrCl, which crystallizes with the symmetry of the monoclinic space group P21/c, has been determined by equiinclination Weissenberg single-crystal X-ray diffraction techniques. The theoretical density...