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Since this landmark study, high-throughput electron-microscopic techniques have enabled reconstructions of much larger mammalian brain circuits at synaptic resolution2,3. Nevertheless, it remains unknown how the structure of a synapse relates to its physiological transmission strength—a key limitation for...
These synapses support essential functions such as sensory perception and overall bodily coordination. In humans, the majority of synapses utilize chemical transmission. A typicalchemical synapsecomprises a presynaptic terminal, asynaptic cleft, and a postsynaptic membrane equipped with neurotransmitter receptor...
STRUCTURE AND CYTOCHEMISTRY OF SYNAPTIC CLEFT - ScienceDirect There is a fact that the most considerable part of the synapse is the material in the synaptic cleft. At the method for the demonstration of proteinaceous ... W Ovtscharoff - 《Synaptic Constituents in Health & Disease》 被引量: ...
Assuming that these inhomogeneities are in fact arc-like shells ejected episodically by the star, a typical mass-loss timescale of ~1000 years is derived.doi:10.1016/S0168-0102(98)82469-3Takahisa TaguchiKen-Ichi OkamotoKazuyuki KiyosueELSEVIER...
Synaptic vesicles are organelles with a precisely defined protein and lipid composition1,2, yet the molecular mechanisms for the biogenesis of synaptic vesicles are mainly unknown. Here we discovered a well-defined interface between the synaptic vesicle
We endeavored to harvest new data on the developmental appearance and spatiotemporal distribution of synapse-rich compartments in a specific cortical region, which can be used for future studies into functional, behavioral and molecular development of a normal cortex. In addition, these new multiscale...
C. Latrophilin GPCR signaling mediates synapse formation. eLife https://doi.org/10.7554/eLife.65717 (2021). Xiao, X. et al. A new understanding of GHSR1a—independent of ghrelin activation. Ageing Res Rev. 64, 101187 (2020). Article CAS PubMed Google Scholar Tao, Y. X. Constitutive ...
Neuroserpin is a serine protease inhibitor identified in a search for proteins implicated in neuronal axon growth and synapse formation. Since its discover