Here we studied a putative CIS gene cluster in the marine bacterium Algoriphagus machipongonensis. Using an integrative approach, we show that the system is compatible with an eCIS mode of action. Our cryo-electron microscopy structure revealed several features that differ from those seen in other...
Brucella melitensis is a pathogenic bacterium responsible for brucellosis in mammals and humans. Its outer membrane proteins (Omp) control the diffusion of solutes through the membrane, and they consequently have a crucial role in the design of diagnostics and vaccines. Moreover, such proteins have ...
Intransformation, the prokaryote takes in DNA found in its environment that is shed by other prokaryotes. If a nonpathogenic bacterium takes up DNA for a toxin gene from a pathogen and incorporates the new DNA into its own chromosome, it too may become pathogenic. Intransduction, bacteriophages,...
The structure, which was obtained from blue crystals, shows a typical ring-shaped bacterial ??-clamp formed of two monomers, each with three domains of identical topology, but with no visible DNA in electron density. A visualisation of the electrostatic surface potential reveals a highly ...
The bacterium possessed a cell wall, cytoplasmic membrane, and nuclear and cytoplasmic regions typical of bacterial cells. Both the cell wall and the cytoplasmic membrane showed a tripartite structure, i.e., each was composed of two dense layers separated by a low-density zone. Intracytoplasmic ...
Self-organization of imidazolium ionic liquids in aqueous solution JustynaŁuczak, ...ChristianJungnickel, inColloids and Surfaces A: Physicochemical and Engineering Aspects, 2008 Analysis of thestructure activity relationship(SAR) of a typical imidazoliumILleads to the assumption thatILscould possess sur...
AtaA, a TAA from the nonpathogenic toluene-degrading bacterium Acinetobacter sp. Tol 521, has unique adhesive properties that are not shared by other reported TAAs; AtaA mediates strikingly tenacious, nonspecific adhesion of the bacterial cells to abiotic surfaces and has dramatically high auto...
Knowledge of cell chemistry is also important in the diagnosis of disease and developing drugs to counteract adverse medical conditions e.g. anti-cancer drugs. What is a cell? A cell is the smallest unit of life able to control its own activities, BUT, it relies on the rest of the organi...
Autotransporters (ATs) are a large family of bacterial secreted and outer membrane proteins that encompass a wide range of enzymatic activities frequently associated with pathogenic phenotypes. We present the structural and functional characterisation of
Cold atmospheric plasma (CAP) has great potential for sterilization in the food industry, by deactivation of thermophilic bacteria, but the underlying mechanisms are largely unknown. Therefore, we investigate here whether CAP is able to denature/modify p