To address the sequence-function gap many computational methods have been developed with the goal to automatically predict protein function. Further, related work is directed at predicting function in a site- or
ProMOL, a plugin for the PyMOL molecular graphics system, is a structure-based protein function prediction tool. ProMOL includes a set of routines for building motif templates that are used for screening query structures for enzyme active sites. Previously, each motif template was generated manually...
I-TASSER-MTD: a deep-learning-based platform for multi-domain protein structure and function predictionXiaogen Zhou, Wei Zheng, Yang Li, Robin Pearce, Chengxin Zhang, Eric W. Bell, Guijun Zhang & Yang Zhang Nature Protocols volume 17, pages 2326–2353 (2022)Cite this article ...
To address the sequence-function gap many computational methods have been developed with the goal to automatically predict protein function. Further, related work is directed at predicting function in a site- or domain-specific manner21,22,23,24. Traditional machine learning classifiers, such as supp...
Identification of family-specific residue packing motifs and their use for structure-based protein function prediction: I. Method development Protein function prediction is one of the central problems in computational biology. We present a novel automated protein structure-based function predicti... D ...
3D Structure Prediction of a Protein Using NovaFold AI DNASTAR’s NovaFold AI application uses the award-winning AlphaFold 2 algorithm to predict the 3D structure of a protein based on its sequence. Lasergene Protein Overview This video gives an overview of Lasergene Protein, consisting of Prote...
Mostab initioprediction approaches are based on the first principle, which states that, in the natural environment, a protein tends to adopt the structural conformation with the lowest free energy. Thus, structure prediction can be accomplished through minimizing an energy function or directly simulatin...
is focused on the studies that investigate and apply AlphaFold and its predictions in a variety of contexts including prediction of protein structure at the atomic, residue and protein levels, prediction and characterization of protein function, applications to protein design, target prediction, drug de...
Details the expansion of the computational protein structure prediction field Provides step-by-step detail essential for reproducible results Contains key notes and implementation advice from the experts Includes supplementary material: sn.pub/extras Part of the book series: Methods in Molecular Biology (...
Protein subcellular localization prediction based on compartment-specific features and structure conservation. BMC Bioinformatics. 2007; 8 (1):330.Su EC, et al. Protein subcellular localization prediction based on compartment-specific features and structure conservation. BMC Bioinformatics. 2007; 8 :330....