GppNHp and the side chains of Thr35 are shown in the stick model. Full size image Table 1 Data Collection and Refinement Statistics. Full size table Application of the HAG method23 to the State 2* crystal induced a sudden lattice transformation along the a and c axes from 87.97 Å ...
d, Cryo-EM map of the Pol I EC (composite Map C in Table 1), colored according to its subunit composition. Subunits are labeled with the human nomenclature and (below) with the yeast counterpart. e, Structural model of the Pol I EC with the functional subdomains (stalk and heterodimer)...
“Working with a Client with Mild Dissociation–A Case Study (bonus 4)” finally gets to the meat of these issues. This is what I have come here for. I don’t understand why this session is called “mild’ because it’s full blown and horrific. But its emphasis is right what I’m ...
Fig. 3. Chemical cross-links identified in ∼7.8 nm rHDL(A-IM/A-IM) (10) mapped on the proposed model of the small A-IM/A-IM double belt. (A) Symmetric double-belt contains two apoA-IM molecules in a conformation depicted in Fig. 2D. The two-fold symmetry axis passes through ...
The temperature effects have been studied at shear rates up to 150 s−1 for fluid samples with the same asphaltene concentration of 40.1 g/l. Each flow curve has been analysed using a two-step procedure. At the first step, the Bingham model (Eq. (2)) has been applied in the whole ...
(1968), Trudgill has developed a model for dialect contact in which the notion of salience plays a central role. Salience is defined in terms of four parameters: stigmatization (the more stigmatized, the more salient), linguistic change (the more directly involved in change, the more salient)...
MD simulations were performed using a simple point-charge (SPC) water model. A certain number of solvent molecules were replaced by Na+ or Cl− ions to make each system electrically neutral. Prior to the MD simulation, all systems were subjected to energy minimization (1000 conjugate gradient...
In our model, the adverse effect of VPA may be derived from a persistent effect on the temporal lobe as it undergoes a protracted and delayed maturation. For example, VPA has been frequently used in infants to manage seizure [44]. Nevertheless, the importance of our experimental approach is ...
The crystal structure of the soluble form of Mt-DsbA was solved by molecular replacement utilizing the model of Bs-BdbD (PDB ID: 3EU3 [39]), which shares 20% sequence identity with Mt-DsbA, combined with the location of two selenium atoms determined from the anomalous data. The structure...
Cation-pi interactions with a model for the side chain of tryptophan: structures and absolute binding energies of alkali metal cation-indole complexes. Threshold collision-induced dissociation techniques are employed to determine bond dissociation energies (BDEs) of mono- and bis-complexes of alkali ...