Structural interactions of mitochondrial ATP synthasome componentsElsevier BVBiochimica et Biophysica Acta (BBA) - BioenergeticsH. NskováT. MikulováM. VrbackT. MráekJ. Houtěk
Circular effects in representations of an RNA nucleotides data set in relation with principal components analysis During the last few years, the main reason for using molecular structure databases has changed. Instead of using databases as a storage medium, databases n... TH Reijmers,R Wehrens,...
This review compares the subunits of the mitochondrial F-ATP synthase, which have been characterized and classified in yeast and mammals, with those identified in plants, discussing the components that have been suggested to be plant specific. Furthermore, the consequences of alterations of some F-...
The Gabija bacterial defense system is a newly discovered bacterial immune defense system contains two components, GajA and GajB. The previous study shows that GajA is essential for bacterial immunity against certain bacteriophages and GajB is also indispensable for Gabija system. GajA is a sequence...
The channel is assembled of four subunits and contains two main components: a TMD with a central ion channel pore and an intracellular skirt that is mostly built of ankyrin repeat domains connected to each other by three-stranded β-sheets, N-terminal helices, and C-terminal hooks. Amphipathic...
Generally, the substrate specificity of these machines is determined by chaperone components, such as ClpA. In some cases, however, the specificity is modified by adaptor proteins, such as ClpS. Here we report the 2.5 A resolution crystal structure of ClpS in complex with the N-terminal domain...
The domain structure explains how the S components with large overall structural differences can interact with the same ECF module while at the same time specifically bind very different substrates with subnanomolar affinity. Solitary BioY (in the absence of the ECF module) is monomeric in detergent...
The mammalian mitochondrial (mt) genome codes for only 13 proteins, which are essential components in the process of oxidative phosphorylation of ADP into ATP. Synthesis of these proteins relies on a proper mt translation machinery. While 22 tRNAs and 2 rRNAs are also coded by the mt genome,...
The ATP binding cassette (ABC) transporters superfamily is one of the largest classes of membrane proteins. The core of the ABC transporter protein is composed of transmembrane domains (TMDs) and nucleotide binding domains (NBD). Eukaryotes ABC transport
To better understand the conformational changes of the apo and ATP-bound IRAK4 KD structures, the MD trajectories of each system were inspected with the principal components. Approximately, the first 15 modes contribute greatly to the collective motions, as only the first 15 eigenvectors showed valu...