Structural connectivity can be evaluated using a technique known as fiber tracking or tractography28,29,30, which constructs a model of the paths of white matter fibers based on the directionality of water diffusion through the white matter. By overlaying a brain atlas of one’s choice, the con...
The implication of this pattern is that the many networks in hindbrain are constructed from a series of neuronal components organized into stripes that are ordered from top to bottom according to a neuron's age, structural and functional properties, and behav- ioral roles. This simple ...
As membrane and organelle proteins are major structural and functional components of several cell signalling pathways, we decided to investigate here the ... Mélodie Malécot and Karim Mezhoud and Arul Marie and Danièle Praseuth and Simone Puiseux-Dao and Marc Edery - 《Aquatic Toxicology》 被引...
The exact role of tau deposition and spreading in neuronal cell death remains unclear. It is currently suspected that tau amyloid fibrils or their precursors aberrantly interact with cellular components including lipids, nucleic acids, proteins, and other cellular components, leading to their role in ...
Of course, structural components may be disrupted with age, but as an effect, not cause of cognitive aging. Even among the genes regulating the timing of development, only a subset of these is expected to influence aging and identifying them will be a major challenge (see below). View ...
19,21 Second, heritable connectivity features that are also pertinent to the symptoms of ADHD can be determined. Finally, the family-based design allowed us to answer the question: Do components of the structural and functional connections share genetic determinants or are they genetically distinct?
TDP-43-immunoreactive inclusions comprised two components: granular and filamentous. Filament widths, expressed as mean (range) were: NCI, 9 nm (4-16 nm); DN, 10 nm (5-16 nm); NII, 18 nm (9-50 nm). Morphologically distinct inclusion components may reflect the process of TDP-43 ...
Searle SRCasella GMcCulloch CE Variance Components. New York, NY John Wiley & Sons Inc1992; 27. Finch DMNowlin NLBabb TL Demonstration of axonal projections of neurons in the rat hippocampus and subiculum by intracellular injection of HRP. Brain Res. 1983;271201- 216Google ScholarCrossref 28...
The cytoplasmic SMN complex consists of nine proteins named SMN, Gemin2-8, and Unrip4. A study analyzing the importance of individual SMN complex components revealed that SMN and Gemin2-4 are essential for Sm core assembly15. SMN and Gemin2 directly associate with Sm proteins bound to the ...
Pain mechanisms: a new theory. Science 150, 971–979 (1965). Article CAS Google Scholar Foster, E. et al. Targeted ablation, silencing, and activation establish glycinergic dorsal horn neurons as key components of a spinal gate for pain and itch. Neuron 85, 1289–1304 (2015). Article ...