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The human brain’s volume is about equal parts gray matter and white matter. Unlike gray matter, which mainly contains densely packed cell bodies of neurons and glia, white matter is almost exclusively made up of bundles of myelinated axons1. The primary purpose of myelin is to considerably ...
have stimulated considerable interest among researchers in natural drug antidepressant therapies. Natural medications have the characteristics of fewer adverse reactions, significant therapeutic effects, and the ability to function in synergy with multiple components. Compared...
we calculated the genetic correlation using the GWAS summary statistics to examine genetic covariance between the multimodal BAGs and 16 clinical traits. The selection procedure and quality check of the GWAS summary statistics are detailed in Method 4E. These traits encompassed ...
After the discovery that the complement system can be activated in the brain by several senile plaques and neurofibrillary tangle related components, in the absence of antibodies, and that neurons are a source of complement proteins in the brain, the involvement of the complement system in AD has...
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Malchiodi, C. (2011). Handbook of art therapy. New York, NY: Guilford. Markram, H., and Tsodyks, M. (1996). Redistribution of synaptic efficacy between neocortical pyramidal neurons. Nature 382, 807–810. doi: 10.1038/382807a0
protein and lipid components of the cells of origin [143]. Exosomes gained attention as a potential vehicle for drug delivery to the brain after a breakthrough study demonstrated exosome-dependent and targeted delivery of therapeutic siRNA into neurons, microglia and oligodendrocytes using intravenous ...
Humans have an exceptional ability to cooperate relative to many other species. We review the neural mechanisms supporting human cooperation, focusing on the prefrontal cortex. One key feature of human social life is the prevalence of cooperative norms t
Machine learned interatomic interaction potentials have enabled efficient and accurate molecular simulations of closed systems. However, external fields, which can greatly change the chemical structure and/or reactivity, have been seldom included in curr