analysis [29]. The success of each algorithm depends on the SV type and size, and all are sensitive to the quality of the reference genome and other factors. For example, the RD approach is the most used and has successfully identified SV using short reads in pigs previously [30,31], b...
local adaptation, and phenotypic variations in livestock [5,6,7,8], but whole-genome characterizations of SVs and their functions have been rare. The genusOvisandCaprafirst diverged at the late Miocene (e.g., 10.96 ± 0.73 Ma) during the adaptive ...
In this study, we examine the roles of SVs in the climate adaptation of these two cattle lineages by generating highly contiguous chromosome-scale genome assemblies. Comparison of the two assemblies along with 18 Mongolian and Hainan cattle genomes obtained by long-read sequencing data provides a c...
Rhodopsin is a prototypical G protein-coupled receptor (GPCR) critical for vertebrate vision. Research on GPCR signaling states has been facilitated using llama-derived nanobodies (Nbs), some of which bind to the intracellular surface to allosterically m
Thermophiles | Definition & Examples from Chapter 1 / Lesson 16 82K Explore an in-depth definition of thermophiles and learn why life on other planets is likely to be thermophiles. Discover thermophile examples and applications. Re...
change of pre-stretch in the second and third segments of the aorta, going from proximal to distal zone. Regarding group assignment, a significative effect of the hypoxia over the pre-stretch values is observed, where both hypoxic groups present differences regarding the control animals. ...
while category X drugs are those that should not be used in pregnant persons because studies in animals or humans have shown fetal abnormalities, and these risks outweigh any potential benefits42. In addition, using DrugShot41, we queried each CDC birth-defect term through PubMed to extract Pub...
Although fewer studies of structural variation have been performed in dogs compared to studies using SNPs or microsatellite loci, some examples of copy number variants (CNVs) that affect phenotype have been identified [2, 16, 17]. To date, four large-scale surveys of structural variation in ...
Selective (natural and human-imposed) and non-selective forces (demographic events and introgression) have driven changes within the pig genome. Their combined effects have created extensive phenotypic diversity and genetic adaptation to local environments across the globe within the modern pig breeds. ...
(boxes within boxes). The distribution of these groups showed no recognisable pattern or association with anatomical features either within or between different whole mount preparations of the pulmonary vein (n = 7, two other examples are shown in Fig. S3). In particular, there was not a...