Uchil RR, Kohli GS, Katekhaye VM, Swami OC. Strategies to combat antimicrobial resistance. J Clin Diagn Res. 2014; 8 :1–4.Uchil RR, Kohli GS, Katekhaye VM, et al. Strategies to combat anti- microbial resistance. J Clin Diagn Res 2014;8:ME01-04....
In this context, this review presents a panel of promising and potential strategies to combat antibiotic resistance/resistant bacteria. Different types of direct-acting and indirect resistance breakers, such as efflux pump inhibitors, antibiotic adjuvants, and oxidative treatments are discussed. In ...
She noted the challenges in antimicrobial research and development (R&D) investment and advocated for innovative approaches, including biologics and advanced diagnostics, to combat antimicrobial resistance. “Real-world evidence data is great because one of the things that it allows us to do is reall...
antibiotics Review Strategies to Combat Multidrug-Resistant and Persistent Infectious Diseases Olga Pacios 1,2 , Lucia Blasco 1,2 , Inès Bleriot 1,2 , Laura Fernandez-Garcia 1,2 , Mónica González Bardanca 1,2, Antón Ambroa 1,2, María López 1,3, German Bou 1,2,4 ...
This review provides a summary of phage-inspired strategies to combat AMR. We firstly cover the phage diversity, and then explain the biological principles of phage therapy that support the use of phages in the post-antimicrobial era. Furthermore, we state the versatility methods of phage therapy...
REVIEWS Anti-virulence strategies to combat bacteria-mediated disease David A. Rasko* and Vanessa Sperandio‡ Abstract | Antibiotic resistance is one of the greatest challenges of the twenty-first century. However, the increasing understanding of bacterial pathogenesis and intercellular communication has...
MRSA remains the solitary of the utmost common antimicrobial resistance diseases or hospital-acquired infections towards severe illness and fatality in the global population [25]. However, there has been a breakthrough in developing novel antibiotics, still effective technologies to combat MRSA are much...
Dual-acting hybrid antibiotics: a promising strategy to combat bacterial resistance. Expert Opin. Drug Discov. 5, 883–902 (2010). Article CAS PubMed Google Scholar Hagihara, M., Crandon, J. L. & Nicolau, D. P. The efficacy and safety of antibiotic combination therapy for infections ...
Antibiotic resistance is projected as one of the greatest threats to human health in the future and hence alternatives are being explored to combat resistance. Antimicrobial peptides (AMPs) have shown great promise, because use of AMPs leads bacteria to develop no or low resistance. In this revie...
to antibiotics; while drug makers may stand athwart their prey declaring 'Resistance is futile!', in fact antibiotic introductions constitute a classic case of nascentes morimur, where the best we can do is keep our current antimicrobial armamentarium a step or two ahead of the pathogens until ...