2006-01-03 STIM1就是钙池调控钙离子通道(store-operated channels)吗? 2005-11-22 微观蛋白传导孔道 2005-11-15 一个重 … kimberye.bokee.com|基于6个网页 3. 钙池调控钙离子通道理论 ... calcium influx),也就是现在常称的钙池调控钙离子通道理论(store-operated channels)。
Capacitative calcium entry is a process whereby depletion of Ca 2+ from intracellular stores leads to the activation of Ca 2+ channels in the plasma membrane and accelerated entry of Ca 2+ into the cytoplasm of cells. Current research focuses on the molecular nature of the channels and the ...
Store-operated Ca++Channels 2933-Pos Store-Operated Ca2+-Induced Ca2+Release Amplifies Cytosolic Ca2+ Signaling and Prevents Store Refilling in Jurkat T Cells Sepehr Dadsetan1,Liudmila Zakharova1,Tadeusz F. Molinski2,Alla F.Fomina1 1University of California Davis,Davis,CA,USA,2University ...
Store-operated calcium channels (SOCs) are a major pathway for calcium signaling in virtually all metozoan cells and serve a wide variety of functions ranging from gene expression, motility, and secretion to tissue and organ development and the immune response. SOCs are activated by the depletion...
In this review, we describe the properties of airway store-operated channels and their role in regulating airway epithelial cell function. This article is part of the themed issue 'Evolution brings Ca2+ and ATP together to control life and death'. 展开 ...
Inhibitors of mitochondrial oxidative metabolism have been proposed to interfere with Ca2+ influx mediated by store-operated channels (SOC), secondary to their effects on ATP production. We assessed SOC activity by 45Ca2+ influx and fluorimetric measurements of free Ca2+ or Mn2+ quench in thapsigarg...
that glioblastoma stem cells express store-operated channels (SOC) that support calcium entry into these cells. Pharmacological inhibition of SOC dramatically reduces cell proliferation and stem cell self-renewal in these cultures. By identifying SOC as a critical mechanism involved in the maintenance of...
Depletion of Ca stores activates store‐operated channels (SOCs), which mediate Ca entry pathways that regulate cellular processes such as contraction, proliferation and gene expression.In vascular smooth muscle cells (VSMCs), stimulation of SOCs composed of canonical transient receptor potential channel...
In many animal cells, store-operated Ca(2+) release-activated Ca(2+) (CRAC) channels function as an essential route for Ca(2+) entry. CRAC channels control many fundamental cellular functions including gene expression, motility, and cell proliferation, are involved in the etiology of several ...
Acta Pharmacologica Sinica 2006 Jul; 27 (7): 813–820 Invited review Store-operated calcium channels and pro-inflammatory signals Wei-chiao CHANG1 Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK Key words calcium channels; store-operated Ca2+ entry; capacitative ...