Store-operated calcium channels (SOCCs) are calcium-selective cation channels. Recently, there has been explosive growth in establishing the molecular mechanisms that mediate store-operated Ca(2+) entry (SOCE) and the role of this process in normal cellular function and disease states. SOCCs and...
To refill the depleted Ca2+stores in theSR, another type of Ca2+channels in the cell membrane, known as store‐operated Ca2+channels (SOCC), are activated. TheseSOCCs are verapamil and nifedipine resistant, but areSKF96465 (SK) and gadolinium (Gd3+) sensitive. BothSKand Gd3+have been ...
Compelling evidences have demonstrated that Ca2+might also enter through other cationic channels such as Store-Operated Ca2+Channels (SOCCs), involved in several physiological functions and pathological conditions. The opening of SOCCs is regulated by the filling state of the intracellular Ca2+store, ...
Store-operated Ca2+ channels (SOCCs) were first identified in non-excitable cells by the observation that depletion of Ca2+ stores caused increased influx ... Yue-kun,Ju,and,... - 《Heart Lung & Circulation》 被引量: 91发表: 2007年 Store-operated calcium entry and the localization of STI...
Xenopus oocyte resting potential, muscarinic responses and the role of calcium and guanosine 30,50-cyclic monophosphate. J. Physiol. 352, 551–574 (1984). 54. Lemonnier, L. et al. Ca2 þ modulation of volume-regulated anion channels: evidence for colocalization with store-operated channels. ...
A calcium channel, such as TRP, may be complexed with other signaling proteins, rather than at a distance in the membrane, to facilitate rapid responses to local changes in Ca2+ concentration, which might not be possible otherwise. It will be interesting to learn whether other ion channels ...
In most instances, the mobilization of Ca2+ from this store is followed by a delayed and sustained uptake of Ca2+ through Ca2+-permeable channels of the cell surface named store-operated Ca2+ channels (SOCCs). This gives rise to a store-operated Ca2+ entry (SOCE) that has been thoroughly...
store-operated calcium entryvascular smooth muscleZDFDiabetes is a major risk factor for cardiovascular disease, affecting both endothelial and smooth muscle cells. Store-operated Ca2+ channels (SOCCs) have been implicated in many diabetic complications. Vascular dysfunction is common in patients with ...
Previous studies have demonstrated that besides the classic canonical transient receptor potential channel family, Orai family and stromal interaction molecule 1 (STIM1) might also be involved in the regulation of store-operated calcium channels (SOCCs). An increase in cytosolic free Ca 2+ ...
A. Bouron Neuronal store-operated calcium channels Mol. Neurobiol., 60 (8) (2023), pp. 4517-4546, 10.1007/s12035-023-03352-5 View in ScopusGoogle Scholar Clemens and Lowell, 2015 R.A. Clemens, C.A. Lowell Store-operated calcium signaling in neutrophils J. Leukoc. Biol., 98 (4) (20...