Peripheral myelin protein 22 modulates store-operated calcium channel activity, providing insights into Charcot-Marie-Tooth disease etiologySchwann cellsCharcot-Marie-Tooth disease (CMT)stromal interaction molecule 1 (STIM1)calcium release-activated calcium channel protein 1 (ORAI1)...
Oligomerization and dynamic clustering underlying activity of store-operated calcium channels. Store-operated Ca2+ entry is initiated by depletion of Ca2+ from the endoplasmic reticulum (ER). Upon depletion, the ER Ca2+ sensor STIM1 oligomerizes, pro... ED Covington - Stanford University.; 被引...
Down-regulation of AβPP enhances both calcium content of endoplasmic reticulum and acidic stores and the dynamics of store operated calcium channel activity J. Alzheimers Dis, 34 (2013), pp. 407-415 CrossrefView in ScopusGoogle Scholar 50 E. Stieren, W.P. Werchan, A. El Ayadi, F. Li...
Moreover, functional mitochondria are required to sustain CRAC channel activity, and downstream transcription factor NFAT translocation[21]. Mechanism of store-operated Ca2+ channel activation The activation mechanism of store-operated Ca2+ chan- nels is one of the most intriguing mysteries. In the ...
/? cells restores SOCE., TRPM7 is not a store-operated calcium channel., TRPM7 kinase rather than channel modulates SOCE., TRPM7 channel activity contributes to the maintenance of store Ca2+ levels at rest., Abstract The transient receptor potential melastatin 7 (TRPM7) is a protein that ...
Calcium-activated K(+) channel (K(Ca)3.1) activity during Ca(2+) store depletion and store-operated Ca(2+) entry in human macrophages. Daut J (2010) Calcium-activated K(+) channel (K(Ca)3.1) activity during Ca(2+) store depletion and store-operated Ca(2+) entry in human macrophage...
STIM1 and Orai1 mediate CRAC channel activity and are essential for human glioblastoma invasion. Pflug. Arch. 2013, 465, 1249–1260. [Google Scholar] [CrossRef] [Green Version] Liu, Z.; Wei, Y.; Zhang, L.; Yee, P.P.; Johnson, M.; Zhang, X.; Gulley, M.; Atkinson, J.M.; ...
such as contraction, proliferation and gene expression.In vascular smooth muscle cells (VSMCs), stimulation of SOCs composed of canonical transient receptor potential channel 1 (TRPC1) proteins requires G protein α q subunit (Gαq)/phospholipase C (PLC)β1/protein kinase C (PKC) activity. ...
Genome-wide RNAi screen of Ca2+ influx identifies genes that regulate Ca2+ release-activated Ca2+ channel activity Recent studies by our group and others demonstrated a required and conserved role of Stim in store-operated $Ca^{2+}$ influx and $Ca^{2+}$ release-activate... Zhang, SL,Yero...
Hypoxia increases AP-1 binding activity by enhancing capacitative Ca[sup 2+] entry in human pulmonary artery endothelial cells. Am J Physiol Lung Cell Mol ... Fantozzi,Ivana,Shen,... - 《American Journal of Physiology Lung Cellular & Molecular Physiology》 被引量: 287发表: 2003年 WFS1 prote...