Store-operated Ca2+ channelsEndoplasmic reticulumMaitotoxin2-APBLiver cells possess store-operated Ca 2+ channels (SOCs) with a high selectivity for Ca 2+ compared with Na +, and several types of intracellular messenger-activated non-selective cation channels with a lower selectivity for Ca 2+ (...
Store-operated calcium channels (SOCs) are a major pathway for calcium signaling in virtually all metozoan cells and serve a wide variety of functions ranging from gene expression, motility, and secretion to tissue and organ development and the immune response. SOCs are activated by the depletion...
Store-Operated Ca2+ Channels (SOCs) are voltage-independent Ca2+ channels activated upon depletion of the endoplasmic reticulum (ER) Ca2+ stores. Early studies suggest the contribution of such channels to Ca2+ homeostasis in insulin-secreting pancreatic β-cells. However, their composition and contrib...
Store-operated Ca++Channels 2933-Pos Store-Operated Ca2+-Induced Ca2+Release Amplifies Cytosolic Ca2+ Signaling and Prevents Store Refilling in Jurkat T Cells Sepehr Dadsetan1,Liudmila Zakharova1,Tadeusz F. Molinski2,Alla F.Fomina1 1University of California Davis,Davis,CA,USA,2University ...
Store-operated Ca2+ Entry Mediated by Orai1 and TRPC1 Participates to Insulin Secretion in Rat β-Cells 来自 Semantic Scholar 喜欢 0 阅读量: 31 作者:J Sabourin,LL Gal,L Saurwein,JA Haefliger,F Allagnat 摘要: Store-operated Cachannels (SOCs) are voltage-independent Cachannels activated upon...
SOCs: store operated calcium channels TG: thapsigargin ATP: adenosine triphosphate SiRNA: small interfering RNA FLSs: fibroblast like synoviacytes STIM1: stromal interaction molecule 1 ORAI1: calcium release-activated calcium channel protein 1 References Prakriya M, Lewis RS. Store-operated...
Store-operated Ca2+ entry (SOCE), which is initiated by the depletion of intracellular Ca2+ stores, is an important pathway in nonexcitable cells [6]. SOCE is mediated by store-operated Ca2+ channels (SOCs), including stromal interacting molecule-1 (STIM1) and Orai1. The vast majority of...
Depletion of intracellular Ca 2+ stores induces Ca 2+ influx across the plasma membrane through store-operated channels (SOCs). This store-operated Ca 2+ influx is important for the replenishment of the Ca 2+ stores, and is also involved in many signaling processes by virtue of the ability ...
The coupling mechanism between endoplasmic reticulum (ER) Ca stores and plasma membrane (PM) store-operated channels (SOCs) remains elusive . STIM1 was shown to play a crucial role in this coupling process ; however, the role of the closely related STIM2 protein remains undetermined. We reveal...
TRPC channels as STIM1-regulated store-operated channels Receptor-activated Ca 2+ influx is mediated largely by store-operated channels (SOCs). TRPC channels mediate a significant portion of the receptor-activate... PF Worley,W Zeng,GN Huang,... - 《Cell Calcium》 被引量: 640发表: 2007年 ...