1993. Analysis of the earliest steps of hepadnavirus replication: genome repair after infectious entry into hepatocytes does not depend on viral polymerase activity. J. Virol. 67 : 4867-4874. [ PMC free article ] [ PubMed ]Kock J, Schlicht HJ. Analysis of the earliest steps of hepadna...
The nature of the initial interactions of African swine fever (ASF) virus with target cells is only partially known, and to date only the ASF virus protein p12 has been identified as a viral attachment protein. More recently, antibodies to viral proteins p54 and p30 have been shown to neutra...
HIV-1 uses cellular co-factors for virion formation and release. The virus is able to incorporate into the viral particles host cellular proteins, such as tetraspanins which could serve to facilitate HIV-1 egress. Here, we investigated the implication of
Hepatitis C virus (HCV) genome replication is thought to occur in a membranous cellular compartment derived from the endo-plasmic reticulum (ER). The molecular mechanisms by which these membrane-associated replication complexes are formed during HCV infection are only starting to be unraveled, and bo...
Enteroviruses, a genus in the family of Picornaviridae,are small non-enveloped animal viruses with a messenger-sense genomic RNA and an icosahedral capsid composed of 60 copies each of four structural proteins.1 There are about 70 different serotypes of
ScienceDirect® is a registered trademark of Elsevier B.V. Cookies are used by this site. To decline or learn more, visit our Cookies page Switch to Mobile Site Recommended articles Avian sarcoma and leukosis virus-receptor interactions: From classical genetics to novel insights into virus...
Accomplishing a feat that had been a pipe dream for decades, scientists have recreated in a test tube the first steps of infection by HIV (human immunodeficiency virus), the virus that causes AIDS (acquired immunodeficiency syndrome). Doing so has provided up-close access to the virus—which ...
3f). Consistent with the immunofluorescence assay results, the expression of NS3 protein was significantly reduced in cells treated at early and late stages, although the inhibition was more pronounced in cells treated at the early stage of virus replication than in those treated after 6 h p....
Virus scanning recommendations for Enterprise computers that are running currently supported versions of Windows Event ID 2108 and Event ID 1084 occur during inbound replication of Active Directory in Windows 2000 Server and in Windows Server 2003 Recommended file and folder exclusions for Microsoft Fo...
In this regard, the main protease (Mpro) has emerged as an essential drug target as it plays a vital role in virus replication and transcription. In this research, we have identified two novel potent inhibitors of the Mpro (PubChem3408741 and PubChem4167619) from PubChem database by ...